Table 5 Summary of the amount of 64Cu radioactivity and NOTA-B11-antibody fragments used in the chelation reactions.

From: Synthesis and evaluation of anti-PD-L1-B11 antibody fragments for PET imaging of PD-L1 in breast cancer and melanoma tumor models

Antibody fragment type

64Cu radioactivity in chelation reaction

Amount of NOTA-B11-antibody fragment in a chelation reaction (µg)

Amount of NOTA-B11-antibody fragment in a chelation reaction (nmol)

µCi

MBq

B11-diabody

522.00 ± 6.24 (n = 3)

19.31 ± 0.23 (n = 3)

20 (n = 3)

0.4 (n = 3)

B11-scFv

514.75 ± 17.74 (n = 4)

19.31 ± 0.46 (n = 4)

20 (n = 4)

0.50 ± 0.20 (n = 4)

B11-nanobody

616.75 ± 324.22 (n = 4)

22.82 ± 12 (n = 4)

40 (n = 4)

2.67 (n = 4)