Table 1 Characteristics of pre-diagnostic cases and their matched controls, along with samples obtained at the time of surgery.
From: Blood based metabolic markers of glioma from pre-diagnosis to surgery
Patient and sample characteristics | ||
|---|---|---|
Pre-diagnosis | Cases | Controls |
Subjects, n | 126 | 126 |
Sex, n (%) | ||
Female | 80 (63.5) | 80 (63.5) |
Male | 46 (36.5) | 46 (36.5) |
Age at sampling (years), mean (range) | 54.3 (28.6–73.6) | 54.3 (27.8–73.0) |
Time from sampling to diagnosis (years), mean (range) | 3.8 (0.15–7.98) | n/a |
Sampling date (year), median (range) | 1999 (1988–2014) | 1999 (1988–2014) |
Time in freezer (years), mean (range) | 19.3 (5.8–31.3) | 19.3 (5.8–31.3) |
BMI (kg/m2), mean (range) | 25.6 (18.3–39.8) | 25.5 (18.1–35.0) |
Fasting status, n | ||
0–4 h | 42 | 45 |
4–6 h | 11 | 8 |
> 8 h | 73 | 73 |
Glioma subtype, n (females/males) | ||
Glioblastoma: 9440/3 | 79 (45/34) | n/a |
Gliosarcoma: 9442/3 | 1 (0/1) | n/a |
Astrocytoma: 9400/3, 9401/3 | 24 (19/5) | n/a |
Oligodendroglioma: 9450/3, 9451/3 | 16 (11/5) | n/a |
Glioma NOS: 9380/3 | 6 (5/1) | n/a |
At surgery | Cases | Cases with < 7 years to pre-diagnostic sample |
Subjects, n | 40 | 27 |
Sex, n (%) | ||
Female | 17 (42.5) | 11 (40.7) |
Male | 23 (57.5) | 16 (59.3) |
Age at diagnosis (years), mean (range) | 62.0 (43.8–77.3) | 62.6 (43.8–77.3) |
Glioma subtype, n (females/males) | ||
Glioblastoma: 9440/3 | 29 (11/18) | 21 (8/13) |
Gliosarcoma: 9442/3 | 1 (0/1) | 0 |
Astrocytoma: 9400/3, 9401/3 | 5 (3/2) | 4 (2/2) |
Oligodendroglioma: 9450/3, 9451/3 | 5 (3/2) | 2 (1/1) |
