Fig. 3
From: BUB1 induces AKT/mTOR pathway activity to promote EMT induction in human small cell lung cancer
Analyses of the in vivo functions of BUB1. (A) Schematic overview of the zebrafish xenotransplantation assay design used in this study. (B) The impact of si-BUB1 transfection on SCLC tumorigenesis in zebrafish, revealing a smaller fluorescent tumor area in the si-BUB1 group at 48Â h relative to the control group. CM-Dil-stained SBC-2 and NCI-H446 cells are shown in red, while zebrafish vascular structures are shown in green. Results are provided as representative images and corresponding quantification.
