Fig. 2
Radiation markers by biological sex and dose. To see the effect of biological sex and dose, significance analysis was performed using the respective groups normalized against untreated same sex controls. Hierarchical cluster analysis using Euclidian distance measure was performed showing the sample grouping by (A) biological sex and (B) dose. The legend shows the colors used for the sample groups (Red for male, Blue for Female) and the scale bar shows the range of the relative intensity values with colors red representing upregulation and blue indicates down regulation. (C) Dot plot of GO biological category compare cluster analysis from clusterProfiler package grouped by biological sex (Male and Female) and dose (HD and LD). The color of dots represents intensity of p-values and size of the dots is relative to gene ratio. Number of significant genes used for each group is shown in parenthesis under each group label.
