Fig. 5 | Scientific Reports

Fig. 5

From: Bioinformatics analysis of immune infiltration in human diabetic retinopathy and identification of immune-related hub genes and their ceRNA networks

Fig. 5

GO/KEGG and GSEA enrichment analysis of DE-mRNA in the GSE160306 dataset. (A) Bubble plot of GO enrichment of DE-mRNAs in dataset GSE160306-mRNA. The most significant BP involved in negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, negative regulation of adaptive immune response, and inflammatory response; CC involved in extracellular matrix, external encapsulating structure, and collagen-containing extracellular matrix; and MF involved in immune receptor activity, and protein homodimerization activity. (B–H) GSEA enrichment analysis of DE-mRNAs from dataset GSE160306-mRNA. DE-mRNAs differentially expressed mRNAs, GO gene ontology, BP biological process, CC cellular components, MF molecular function, GSEA gene set enrichment analysis.

Back to article page