Table 3 Baseline characteristics of the study population.

From: EDNRA affects susceptibility to large artery atherosclerosis stroke through potential inflammatory pathway

Characteristics

LAA(n = 428)

Controls(n = 434)

Unadjusted

Adjusted*

OR (95% CI)

p

OR (95% CI)

p

Age, years

63.33 ± 10.54

58.45 ± 11.71

 

< 0.001

  

Male/female

274/154

189/245

2.306(1.754–3.033)

< 0.001

1.503(1.048–2.157)

0.027

Hypertension, n (%)

321(75.0)

175(40.3)

4.440(3.319–5.939)

< 0.001

2.984(2.158–4.128)

< 0.001

Diabetes, n (%)

180(42.1)

67(15.4)

3.976(2.877–5.494)

< 0.001

2.694(1.886–3.849)

< 0.001

Heart diseases, n (%)

47(11.0)

18(4.1)

2.851(1.627–4.995)

< 0.001

2.421(1.295–4.525)

0.006

Hyperlipidemia, n (%)

288(67.3)

276(63.6)

1.178(0.889–1.560)

0.254

1.041(0.753–1.440)

0.806

Smoking, n (%)

160(37.4)

65(15.0)

3.389(2.440–4.707)

< 0.001

2.329(1.427-3.800)

< 0.001

Drinking, n (%)

129(30.1)

56(12.9)

2.912(2.055–4.126)

< 0.001

1.078(0.650–1.786)

0.771

Overweight, n (%)

238(55.6)

186(42.9)

1.670(1.276–2.186)

< 0.001

1.318(0.966–1.799)

0.082

HHCY, n (%)

282(65.9)

227(52.3)

1.761(1.338–2.318)

< 0.001

1.034(0.743–1.439)

0.843

Carotid stenosis, n (%)

257(60.0)

165(38.0)

2.450(1.863–3.222)

< 0.001

1.450(1.057–1.989)

0.021

  1. Notes: *Adjusted for gender, hypertension, diabetes, heart diseases, smoking status, drinking habits, overweightness, carotid stenosis and HHCY.
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