Fig. 5

Subgroup analyses of PFS. The 5-Fu-DEB-TACE group showed a significantly longer PFS in the subgroup of patients with BCLC stage A (A), BCLC stage (B), multifocal (D), Child-Pugh stage A (F), non- extrahepatic metastasis (J), non-vascular invasion (L), and with a largest tumor diameter ≥ 5 cm (O), whereas no significant difference was found in the other subgroups (C, E, G-I, K, M, N). Kaplan–Meier method and log-rank test were implemented to evaluate the difference of survival between two groups. P < 0.05 was considered significant. DEB-TACE, drug-eluting beads TACE; cTACE, conventional transarterial chemoembolization. BCLC, Barcelona Clinic Liver cancer.