Fig. 1
From: Liver knockout of MCU leads to greater dysregulation of lipid metabolism in MAFLD
The consumption of a high-fat diet leads to a significant increase in both body weight and fat mass in mice (n = 6). (A) Representative images of mice under different treatment conditions; Scale bar: 1 cm. (B) Assessment of liver MCU protein levels in the HFD-MCUfl/fl and HFD-MCU∆hep groups. (C) Measurement of body weights in mice subjected to various treatments. (D) Evaluation of fat mass in mice exposed to different treatments. (E) Analysis of lean mass in mice following treatments. (F) Representative photographs and histological analysis of inguinal fat in mice; Scale bar: 1 cm and 100 µm (40× objective). (G) Relative weight of intra-abdominal white adipose tissue (iWAT) to body weight in different groups of mice. (H) Representative photographs and H&E staining analysis of epididymal fat pads in mice; Scale bar: 1 cm and 100 µm (40× objective). (I) Relative weight of epididymal white adipose tissue (eWAT) to body weight in different groups of mice. The results are presented as means ± standard deviation (SD). Different letters meant there was significant difference among groups (p < 0.05).
