Table 2 Clinical parameters of included participants.

From: Thyroid antibodies in Hashimoto’s thyroiditis patients are positively associated with inflammation and multiple symptoms

Variables

HT group (n = 108)

Control group (n = 57)

P value

TSH, mIU/L

2.55 (1.78, 3.73)

2.19 (1.63, 3.96)

0.283

FT3, pmol/L

4.28 ± 0.47

4.35 ± 0.44

0.513

FT4, pmol/L

14.94 ± 2.59

15.28 ± 2.01

0.366

TPO-Ab, KU/L

178.25 (15.38, 530.62)

0.37 (0.26, 0.48)

 < 0.001

TG-Ab, KU/L

28.49 (2.72, 205.53)

0.26 (0.20, 0.28)

 < 0.001

TC, mmol/L

4.86 ± 0.83

4.45 ± 0.82

0.029

TG, mmol/L

0.96 ± 0.50

0.90 ± 0.36

0.556

LDL-C, mmol/L

2.83 ± 0.71

2.37 ± 0.60

0.003

HDL-C, mmol/L

1.62 ± 0.39

1.37 ± 0.28

0.003

CD3+/total lym, %

70.81 ± 7.16

72.53 ± 6.69

0.278

CD4+/total lym, %

35.37 ± 6.70

36.63 ± 5.66

0.381

CD8+/total lym, %

28.61 ± 7.02

30.43 ± 5.41

0.219

CD4+/CD8+

1.34 ± 0.53

1.25 ± 0.34

0.411

IL-4, pg/mL

0.46 ± 0.30

0.68 ± 0.73

0.043

IL-6, pg/mL

1.40 ± 0.91

1.73 ± 1.19

0.147

IL-10, pg/mL

1.69 ± 0.84

1.76 ± 1.02

0.719

TNF-α, pg/mL

1.25 ± 0.63

0.84 ± 0.73

0.008

IFN-γ, pg/mL

2.08 ± 0.53

0.77 ± 0.73

 < 0.001

IgG, g/L

12.99 ± 2.29

12.82 ± 1.93

0.723

IgM, g/L

1.22 ± 0.42

1.30 ± 0.37

0.418

IgA, g/L

1.85 ± 0.68

1.80 ± 0.61

0.737

ALT, U/L

19.30 ± 18.46

15.52 ± 5.81

0.286

AST, U/L

24.09 ± 10.71

17.13 ± 3.83

 < 0.001

TP, g/L

74.99 ± 4.79

72.99 ± 3.07

0.041

ALB, g/L

46.62 ± 2.67

45.09 ± 1.91

0.007

GLOB, g/L

28.37 ± 3.98

27.90 ± 2.29

0.545

hsCRP, mg/L

0.57 (0.42, 1.03)

0.20 (0.10, 0.54)

 < 0.001

  1. Data are described as counts and percentages for categorical variables, as means and standard deviations for normally distributed variables, and as medians and interquartile ranges for non-normally distributed variables. Abbreviations: HT, Hashintoto’s thyroiditis; BMI, body mass index; TSH, thyroid stimulating hormone; FT3, free triiodothyronine; FT4, free thyroxine; TPO-Ab, antithyroid peroxidase; TG-Ab, antithyroid thyroglobulin; TC, total cholesterol; TG, triglycerides; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TNF-α, tumor necrosis factor α; IFN-γ, interferon γ; IL, interleukin; IgG, immunoglobulin G; IgM, immunoglobulin M; IgA, immunoglobulin A; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TP, total protein; ALB, albumin; GLOB, globulin; hsCRP, high sensitivity C-reactive protein.
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