Fig. 3 | Scientific Reports

Fig. 3

From: Abnormal ac4C modification in metabolic dysfunction associated steatotic liver cells

Fig. 3

Overview of ac4C peaks in control and MASLD model cells. (A) Distribution of ac4C sites on transcriptome in control and MASLD model cells. (B) The number of ac4C peaks spanning different number of exons in control and MASLD model cells. (C) The number of transcripts containing different number of ac4C peaks in control and MASLD model cells. (D) Distribution of ac4C peaks occurring within CDS or UTRs in mRNA and lncRNA regions in control and MASLD model cells. (E) The distribution of ac4Cs on mRNA in control and MASLD model cells within the 5′ UTR, CDS, start codon, stop codon, TSS, and 3′ UTR. (F) The overlaps and differences of ac4C peaks and ac4C modified transcripts between control and MASLD model cells. (G) The sequence logo of the top 5 differential mode motifs of ac4Cs from control and MASLD model cells.

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