Fig. 2
CBS-H2S axis alleviated intestinal barrier disruption and maintained intestinal epithelial proliferation in UC. (A, B) H&E staining of colon tissue of WT and CBS +/− mice at day 7 (40x, 100 × and 400x). (C, D) Inflammation score of colon tissue of WT and CBS + /- mice. (E, F) Comparison of inflammation score of colons between WT and CBS +/− mice in DSS group and DSS + GYY4137 group. (G) FD-4 flux of intestine of WT and CBS +/− mice at day 7. (H, I) Colon length between WT and CBS +/− mice at day 7. (J, K) Ki67 IHC staining of lower colon (near rectum) epithelial tissue between WT and CBS +/− mice induced by DSS after 7 days.
