Table 3 The logistic regression analysis for the Tinnitus Handicap Inventory (THI) grades 2–5.

From: KCNQ4 c.546C>G variant is associated with early-onset high-frequency hearing loss, tinnitus, and cardiovascular comorbidities in Taiwanese adults

 

Simple model

Multiple model

OR

(95%CI)

p value

OR

(95%CI)

p value

KCNQ4 vs Control

4.50

(1.60–12.62)

0.004**

3.20

(1.02–10.06)

0.046*

Age

1.06

(1.02–1.11)

0.008**

1.02

(0.97–1.08)

0.391

Female

0.77

(0.28–2.10)

0.613

   

BMI (kg/m2)

1.04

(0.94–1.15)

0.443

   

Cardiovascular disease

3.24

(1.31–7.99)

0.011*

1.13

(0.34–3.80)

0.841

Hypertension

2.74

(0.96–7.80)

0.059

   

DM

2.42

(0.46–12.77)

0.296

   

Hyperlipidemia

3.86

(1.39–10.71)

0.009**

   

SBP ≥ 140 or DBP ≥ 90

0.38

(0.05–3.00)

0.360

   

Family history

1.00

(0.42–2.39)

0.993

   

Noise exposure

7.57

(2.29–25.00)

0.001**

3.24

(0.72–14.66)

0.126

Habits

 Smoking

16.00

(5.01–51.07)

 < 0.001**

5.19

(1.14–23.72)

0.034*

 Drinking

6.58

(2.05–21.11)

0.002**

2.83

(0.55–14.49)

0.211

 Exercise

0.59

(0.24–1.46)

0.255

   
  1. Logistic regression. *p < 0.05, **p < 0.01. BMI, Body mass index; DM, Diabetes mellitus; SBP, Systolic blood pressure.
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