Fig. 6

Metabolite panel segregating Omicron-infected patients of different severity. (A) Plot of test MSE by log (λ) value from lasso analysis that selects significant variables differentiating moderate/severe infections from mild infections amongst Omicron-infected patients (n = 66) based on optimal λ. (B) Three lasso-selected variables that discriminate Omicron-infected patients of different disease severity. (C) Area under receiver operating characteristic curve illustrates the performance of three lasso-selected variables in differentiating Omicron patients of different severity, with age and gender as covariates. AUC, area under the curve; Log, logarithm; ROC, receiver operating curve; FC, fold change; SL, sulfatide; Pro, proline; Tyr, tyrosine; Val, valine.