Table 2 Univariate and multivariate Cox regression analysis of factors associated with OS in LUAD.

From: Effect of defective H2B ubiquitination on the malignancy and repair of DNA double breaks and its significance in lung adenocarcinoma

Clinicopathological

variables

Cox univariate analysis

Coxmultivariate analysis

HR

95%CI

P

HR

95%CI

P

Gender

(Female VS. Male)

2.386

1.124-5. 065

0.024

   

Age (≥ 60 years

VS. < 60 years)

0.678

0.34–1.3 49

0.268

   

Smoking

(YES VS. NO)

0.415

0.208-0. 827

0.012

   

T staging

(T3 + T4 VS. T1 + T2)

0.424

0.219-0. 821

0.011

0.394

0.19–0.8 14

0.012

N staging

(N0 + N1 VS. N2 + N3)

0.482

0.25–0.9 26

0.029

0.356

0.13–0.9 78

0.045

M staging

(M1 VS. M0)

0.595

0.182-1. 941

0.389

   

Clinical staging

(I + II VS. III + IV)

0.447

0.227-0. 884

0.021

   

Lymph node

metastasis (Yes VS. No)

1.41

0.735-2. 708

0.301

   

Recurrence

(YES VS. NO)

2.348

1.224-4. 504

0.01

2.323

1.182-4. 565

0.014

EGFR mutation

(YES VS. NO)

0.72

0.336-1. 542

0.398

   

KRAS mutation

(YES VS. NO)

1.22

0.604-2. 463

0.58

   

uH2B (Low expression

VS. High expression)

0.714

0.252-2. 028

0.527

0.787

0.261-2. 368

0.669

Back to article page