Fig. 4 | Scientific Reports

Fig. 4

From: LAMC3 interference reduces drug resistance of carboplatin-resistant ovarian cancer cells

Fig. 4

Plate cloning assay tested the effects of LAMC3 interference on clone formation of carboplatin-resistant ovarian cancer cells. (a) Clonal formation of carboplatin-resistant ovarian cancer cells from the control group and LAMC3 interference group for 10 day treatment with a series of gradient carboplatin. (b) Image J software analyzed the relative clone formation rate. H-C-C3 Scramble: the carboplatin-resistant ovarian cancer cells transfected with LAMC3 scamble; H-C-C3 shRNA3: the carboplatin-resistant ovarian cancer cells transfected with LAMC3 interference lentivirus. Control: the carboplatin-resistant ovarian cancer cells in H-C-C3 Scramble and H-C-C3 shRNA3 group were not treated with carboplatin. p values < 0.05 were deemed significant, with * representing p < 0.05, **p < 0.01, and ***p < 0.001. Scale bars = 100 μm.

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