Correction to: Scientific Reports https://doi.org/10.1038/s41598-025-98266-8, published online 20 April 2025
The original version of the Article contained an error in Fig. 3. As a result of an error during figure assembly, the shCD147 image in Fig. 3B was mistakenly a duplication of the shNC image.
The original Fig. 3 and accompanying legend appear below.
CD147 knockdown inhibits proliferation and induces apoptosis in CRC cells. (A) CCK-8 proliferation assay showing reduced viability of HCT116 and SW620 cells transfected with shCD147-1 (shCD147) compared to non-targeting control (shNC) at 48 h and 72 h (n = 3, mean ± SD; ***P < 0.001, one-way ANOVA). (B, C) Colony formation assay in shCD147 and shNC groups. (B) Representative images of colonies (crystal violet staining). (C) Quantification of colony numbers (n = 3; ***P < 0.001 vs. shNC, Student’s t-test). (D-F) Western blot analysis of proliferation/apoptosis-related proteins. (D) Representative blots of c-Myc, Bcl-2, and Bax in shCD147 and shNC groups. β-actin served as loading control. Original blots are presented in Supplementary Fig. 2. (E, F) Densitometric quantification of protein levels (n = 3; **P < 0.01, ***P < 0.001 vs. shNC, Student’s t-test). (G, H) Flow cytometry analysis of apoptosis. (G) Representative Annexin V-FITC/PI staining profiles. (H) Quantification of apoptotic cell percentages (n = 3; ***P < 0.001 vs. shNC, Student’s t-test).
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Xiaoxia, F., Rui, L., Meiru, C. et al. Author Correction: CD147 regulates the Rap1 signaling pathway to promote proliferation, migration, and invasion, and inhibit apoptosis in colorectal cancer cells. Sci Rep 15, 20237 (2025). https://doi.org/10.1038/s41598-025-07329-3
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DOI: https://doi.org/10.1038/s41598-025-07329-3
