Fig. 5
From: Membrane proteome analysis identifies key components of sensing in Phytophthora parasitica zoospores
Zoospore membrane receptors. (a) Receptors identified through membrane proteomic analysis of zoospores. (b) AlphaFold model of PPTG_07417 with pLDDT score indicating the accuracy of prediction for each residue. (c) Domain structure of PPTG_07417, positioning the Niemann-Pick C1 ___domain (122–328 aa) coloured in orange, Sterol Sensing ___domain (740–923 aa) in magenta, and Patched ___domain (1273–1450 aa) in green. (d) Structural alignment of PPTG_07417 structure (cyan) with the crystal structure of fulllength human NPC1 (magenta, PDB: 3JD8). RMSD = 14. (e) Bright-field (left), Fluorescence (center) and Merged (right) confocal laser microscopy images of zoospores stained for PPTG_07417.
