Table 1 KEGG pathway enrichment of NTDs relating genes.
KEGG_A_class | KEGG_B_class | Pathway | Gene no | P-value |
|---|---|---|---|---|
Human diseases | Cancers | Pathways in cancer | 11 | 0.0306 |
Environmental information processing | Signal transduction | MAPK signaling pathway | 8 | 0.01487 |
Environmental information processing | Signaling molecules and interaction | Neuroactive ligand-receptor interaction | 8 | 0.03237 |
Organismal systems | Circulatory system | Adrenergic signaling in cardiomyocytes | 7 | 0.00109 |
Organismal systems | Immune system | Platelet activation | 6 | 0.00247 |
Human diseases | Infectious diseases | HTLV-I infection | 6 | 0.03539 |
Organismal systems | Environmental adaptation | Circadian entrainment | 5 | 0.00441 |
Organismal systems | Nervous system | Cholinergic synapse | 5 | 0.00813 |
Organismal systems | Endocrine system | Estrogen signaling pathway | 5 | 0.01665 |
Human diseases | Infectious diseases | Hepatitis B | 5 | 0.03176 |
Organismal systems | Endocrine system | Prolactin signaling pathway | 4 | 0.00922 |
Organismal systems | Endocrine system | Melanogenesis | 4 | 0.02272 |
Organismal systems | Endocrine system | Parathyroid hormone synthesis, secretion and action | 4 | 0.02815 |
Human diseases | Substance dependence | Amphetamine addiction | 4 | 0.00632 |
Human diseases | Cardiovascular diseases | Arrhythmogenic right ventricular cardiomyopathy (ARVC) | 4 | 0.00964 |
Environmental information processing | Signal transduction | ErbB signaling pathway | 4 | 0.01393 |
Environmental information processing | Signal transduction | TNF signaling pathway | 4 | 0.03246 |
Organismal systems | Digestive system | Fat digestion and absorption | 3 | 0.00914 |
Organismal systems | Nervous system | Long-term depression | 3 | 0.02769 |
Metabolism | Amino acid metabolism | Tyrosine metabolism | 3 | 0.00796 |
