Fig. 5
From: Activin A affects colorectal cancer progression and immunomodulation in a stage dependent manner
Activin (+) AOIs display several correlations not observed in activin (-) AOIs. Activin co-localization was associated with the correlation of (A) PD-L1 and Phospho-Tuberin, (B) CD163 and FAP-α, and (C) FOXP3 and Phsopho-p38 MAPK in stage III tissue samples regardless of tissue compartment. (D-F) Similar correlations were observed in stage II activin (+) AOIs. These effects were not observed in activin (-) AOIs (see supplemental Fig. 2). Data analyzed via linear correlation with R-squared values reported to represent the goodness of fit.
