Table 1 Comparison of NPM patient characteristics between PRL level stratified by breast deformity.

From: A cohort study of prolactin and non-puerperal mastitis using real world data

 

With NI

Without NI

Pc

PRL low-normal

PRL high

Pa

PRL low-normal

PRL high

Pb

Total(n)

140

46

 

342

146

  

Demograpic

Age (mean (SD))

34.28 (9.80)

32.30 (7.30)

0.211

31.86 (5.58)

32.14 (5.32)

0.614

0.002

Smoking history (n(%))

 No

127 (90.7)

37 (80.4)

0.107

305 (89.2)

125 (85.6)

0.336

1

 Yes

13 (9.3)

9 (19.6)

 

37 (10.8)

21 (14.4)

  

Crash history (n(%))

 No

58 (41.4)

15 (32.6)

0.374

162 (47.4)

67 (45.9)

0.841

0.088

 Yes

82 (58.6)

31 (67.4)

 

180 (52.6)

79 (54.1)

  

Lab test and medical history (n(%))

Glycemia

 Low-normal

134 (95.7)

45 (97.8)

0.836

326 (95.3)

133 (91.1)

0.11

0.351

 High

6 (4.3)

1 (2.2)

 

16 (4.7)

13 (8.9)

  

ALT

 Low-normal

132 (94.3)

45 (97.8)

0.565

319 (93.3)

131 (89.7)

0.248

0.24

 High

8 (5.7)

1 (2.2)

 

23 (6.7)

15 (10.3)

  

Testosterone

 Low-normal

133 (95.0)

42 (91.3)

0.574

326 (95.3)

142 (97.3)

0.459

0.424

 High

7 (5.0)

4 (8.7)

 

16 (4.7)

4 (2.7)

  

HLP abnormal

 No

77 (55.0)

29 (63.0)

0.433

216 (63.2)

83 (56.8)

0.227

0.354

 Yes

63 (45.0)

17 (37.0)

 

126 (36.8)

63 (43.2)

  

Other (n(%))

Pituitary microadenomas diagnosis

 No

133 (95.0)

40 (87.0)

0.128

340 (99.4)

140 (95.9)

0.016

0.001

 Yes

7 (5.0)

6 (13.0)

 

2 (0.6)

6 (4.1)

  

Relapse

 No

138 (98.6)

44 (95.7)

0.55

331 (96.8)

146 (100.0)

0.063

1

 Yes

2 (1.4)

2 (4.3)

 

11 (3.2)

0 (0.0)

  

Abortion history

 No

139 (99.3)

46 (100.0)

1

338 (98.8)

144 ( 98.6)

1

0.714

 Yes

1 (0.7)

0 (0.0)

 

4 (1.2)

2 (1.4)

  

Hormone supplement history

 No

140 (100.0)

45 (97.8)

0.557

339 (99.1)

143 (97.9)

0.527

0.714

 Yes

0 (0.0)

1 (2.2)

 

3 (0.9)

3 (2.1)

  

Thyroid disease history

 No

138 (98.6)

46 (100.0)

1

335 (98.0)

144 (98.6)

0.887

0.716

 Yes

2 (1.4)

0 (0.0)

 

7 (2.0)

2 (1.4)

  

Mental illness history

 No

139 (99.3)

46 (100.0)

1

340 (99.4)

143 (97.9)

0.324

0.886

 Yes

1 (0.7)

0 (0.0)

 

2 (0.6)

3 (2.1)

  
  1. aP-value of the chi-squared test and ANOVA test between different PRL levels among patients with nipple inversion.
  2. bP-value of the chi-squared test and ANOVA test between different PRL levels among patients with normal breast structure.
  3. cP-value of the chi-squared test and ANOVA test between different breast structure condition.
  4. Glycemia, high level of GLU is higher than 6.1 mmol/L, and others belong to the low-normal level; ALT, high level of ALT higher than 45 IU/L; Testosterone, high level of testosterone is higher than 1.67 nmol/L; HLP abnormal, yes if TG > = 1.7 mmol/L or tCHOL > = 5.72 mmol/L or positive in the previous history of hyperlipidemia or fatty liver disease; Pituitary microadenomas diagnosis, patient’s diagnosis of pituitary microadenomas was yes; Relapse, yes if the patient recurs during the follow-up period; Abortion history, patients who have had a history of abortion within six months before onset were judged as yes; Hormone supplement history, patients who had hormone supplements within six months before onset were judged as yes. Thyroid disease history, patients diagnosed with a history of thyroid disease were judged as yes. Mental illness history, patients diagnosed with a history of mental illness were judged as yes.
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