Fig. 4 | Scientific Reports

Fig. 4

From: Early stage of metabolic dysfunction associated steatotic liver disease disrupts circadian rhythm and induces neuroinflammation in rats

Fig. 4

Effects of High-Fat/High-Cholesterol diet on glucose tolerance after 90 days of feeding. (a) Glycemia evolution over a 3-h period after a 2 g/kg b.w. oral glucose administration. (b) Glycemia kinetic parameters, fasting glycemia and insulin, glycemia measured after 180 min of testing, HOMA IR. Pancreas HES-stained sections images are presented in section (c) Graphs present results of area (d) and length (e) of Langherans’ islets (). Number of islets is presented in graph (f). Data are presented as mean ± SD. Unpaired Student t-test: *p < 0.05 compared to control group (n = 5–6 per group).

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