Fig. 8 | Scientific Reports

Fig. 8

From: Integrated multi-omics analysis and experimental verification reveal the involvement of the PI3K/Akt signaling pathway in myometrial fibrosis of adenomyosis

Fig. 8

Pathway analysis of integrated differentially expressed proteins and metabolites in adenomyosis. (A) IPath pathway analysis of the differentially expressed metabolites and proteins. (B) Heatmap illustrating the quantitative correlation coefficients between proteomics and metabolomics. (C) Heatmap analysis was performed using Spearman correlation analysis, showing the relation between PI3K/AKT pathway protein and DEMs. The color key indicates correlation strengths,* represents P value < 0.05, ** represents P value < 0.01. (D) Relevance network graph depicting correlations derived from Spearman correlation analysis between PI3K/AKT pathway and DEMs.

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