Fig. 6: ECM protein and nuclear YAP expression is enhanced in UUS and ESS tumors with high CFR. | npj Precision Oncology

Fig. 6: ECM protein and nuclear YAP expression is enhanced in UUS and ESS tumors with high CFR.

From: FOXP3+ T cells in uterine sarcomas are associated with favorable prognosis, low extracellular matrix expression and reduced YAP activation

Fig. 6

a, b Representative IHC images and quantification of indicated protein expressions show higher expression in the CFRHigh group in UUS (a) and in ESS patients (b). Scale bars indicate 100 μm. c, d Representative IHC images of YAP expression and quantification of its nuclear/cytoplasmic ratio shows a higher ratio in the CFRHigh patient group in UUS (c) and in ESS patients (d). Upper panels scale bars indicate 100 μm and lower panels scale bars indicate 20 μm. Plots indicate average ± s.d. Significance test is indicated *(P < 0.05), **(P < 0.01).

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