Fig. 1: Overexpression of Rab27A in NSCLC and its effect on prognosis. | npj Precision Oncology

Fig. 1: Overexpression of Rab27A in NSCLC and its effect on prognosis.

From: Targeting TYK2 alleviates Rab27A-induced malignant progression of non-small cell lung cancer via disrupting IFNα-TYK2-STAT-HSPA5 axis

Fig. 1

a The expression data of RAB27A was downloaded from the GEO database (http://www.ncbi.nih.gov/geo) and was analyzed to compare the expression difference between NSCLC tissues (N = 226) and paired normal lung tissues (N = 20) (Microarray ID: GSE31210). b Relative RAB27A mRNA expression level of 115 NSCLC tissues and paired normal lung tissues. c Effect of the Rab27A expression level on the overall survival of NSCLC patients. The expression data and prognostic data were downloaded from the GEO database (Microarray ID: GSE3141). d Formalin-fixed and paraffin-embedded NSCLC tissues and paired normal lung tissues were performed IHC analyses of the Rab27A protein (Scale bar, 100 μm). e Survival analysis of patients in high score group (N = 81) and low score group (N = 87) according to the immunohistochemical score (cut-off value = 8). f Violin plots were generated to show the distribution of the Rab27A cytoscore across different clinical characteristics of patients. *P < 0.05; **P < 0.01; ***P < 0.001.

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