Extended Data Fig. 7: RNA-sequencing analysis for NRVMs transduced with lentivirus expressing control shRNA or Crat shRNA. | Nature Metabolism

Extended Data Fig. 7: RNA-sequencing analysis for NRVMs transduced with lentivirus expressing control shRNA or Crat shRNA.

From: CRAT links cholesterol metabolism to innate immune responses in the heart

Extended Data Fig. 7

a, b, Heatmap and volcano plot of the significantly differential expressed genes. c, d, GSEA analysis of hallmark pathways shows 17 upregulated and 17 downregulated pathways in CRAT knockdown (KD) NRVMs. e. Heatmap analysis of the major enzymes involved in cholesterol biosynthesis pathway.

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