Extended Data Fig. 3: K90-114TAT treatment alters proliferation and apoptosis of GBM tumors. | Nature Cancer

Extended Data Fig. 3: K90-114TAT treatment alters proliferation and apoptosis of GBM tumors.

From: A designer peptide against the EAG2–Kvβ2 potassium channel targets the interaction of cancer cells and neurons to treat glioblastoma

Extended Data Fig. 3

Representative images showing proliferation and apoptosis of G489 xenograft tumors (pHis3: n = 54, cleaved caspase 3: n = 53) or GL261 syngeneic tumors (pHis3: n = 53 and 48, cleaved caspase 3: n = 54) treated with K59-78TAT or K90-114TAT. STEM121 labels G489 tumor cells. GFP labels GL261 tumor cells. pHis3 labels mitotic cells. cleaved caspase 3 labels apoptotic cells. Samples were evenly and independently collected from 3 animals. P values, two-sided unpaired t-test. Error bars, mean ± s.e.m.

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