Extended Data Fig. 8: Over-expression of histones in enterocytes reduces fertility.

a-c, Over-expression of Histones H3/H4 in adult ECs in females (5966GS > H3/H4) reduced the number of progeny, both in flies fed control food (1x SYA) and those fed food with a doubled yeast content (2x SYA) (n = 10 biological replicates of 3 males and 3 females per replicate, (a) students t test, *p < 0.05; (b,c) two-way ANOVA, treatment p < 0.001). Data are presented as mean values ± s.e.m.