Extended Data Fig. 10: Biological safety evaluation of quercetin treatment in mice.

(a) The body weight of mice in four groups. Data are presented as the mean ± SEM. n = 25 for each group (unpaired two-tailed t-test). (b) and (c) The serum level of alanine aminotransferase (ALT) and aspartate transaminase (AST) for liver function. Data are presented as the mean ± SEM. n = 5 for each group (unpaired two-tailed t-test). (d) and (e) The serum level creatinine (CREA) and blood urea nitrogen (BUN) for renal function. Data are presented as the mean ± SEM. n = 5 for each group (unpaired two-tailed t-test). (f) and (g) The serum level of creatine kinase (CK) and lactic dehydrogenase (LDH) for heart function. Data are presented as the mean ± SEM. n = 5 for each group (unpaired two-tailed t-test).