Extended Data Fig. 7: DNA methylation pattern of multi-LT DMRs among various human cancer datasets.
From: Conserved epigenetic hallmarks of T cell aging during immunity and malignancy
(a) Epigenetic age estimation of four cancer patient cohorts based on Horvath DNAm PhenoAge. n = 81 for B-ALL samples, n = 194 for AML samples, n = 89 for melanoma samples. (b) DNA methylation level plots on selected EA genes. (c) Average methylation box plot comparing genome wide methylation versus EA program among healthy controls and cancer patients with B-ALL, AML, melanoma or neuroblastoma. For all box plots, box and hinges correspond to the first, second and third quartiles, upper whisker extends to min(largest value, upper hinge + 1.5 * IQR), lower whisker extends to max(smallest value, lower hinge - 1.5 * IQR).
