Extended Data Fig. 10: The characteristic of developed microbiota-based frailty index (FI-microbiota) and metabolite-based frailty index (FI-metabolite).
From: Gut microbial features and circulating metabolomic signatures of frailty in older adults
a-c, Violin plots showing the distribution of FI-microbiota across four frailty groups (n = 222, 778, 310 and 138 for no, mild, moderate, and severe frailty, respectively) (a) and FI-metabolite across four frailty groups (n = 251, 929, 404 and 187 for no, mild, moderate, and severe, respectively) (c). The upper and lower edges of the boxplot indicate the 75th and 25th percentiles, respectively, and the middle line indicates the median. P values were calculated using two-sided Wilcoxon rank-sum tests. b-d, Heatmap of Spearman correlations between FI-microbiota and its component (b), and between FI-metabolite and its components. The number on each cell is the significant correlation coefficient and the blank cell represents no significant.
