Extended Data Fig. 5: The uterus exhibits different gene expression between young and aging mice.
From: Endometrial aging is accompanied by H3K27ac and PGR loss
a, H3K27ac in the murine uterus (n = 5). b, The percentage of Ki67-positive cells in uterine epithelial and stromal cells (n = 3). c, PCA Plot of murine uterine RNA-seq data (n = 4). d, Volcano plot illustrating gene expression changes between young and aging mice (|log2FC| > 1, P.adj < 0.05). e, Heatmap showing gene expression of DEGs between the young and aging murine uterus. f, Pathway enrichment analysis of upregulated DEGs in the aging murine uterus. In a and b, statistical analysis was performed by two-sided Student’s t-test or Mann–Whitney U rank-sum test. Data are presented as mean ± s.d. All replicates were biological replicates. FC, fold change; P.adj, adjusted P value; PC, principal component; PCA, principal component analysis.
