Fig. 4: Relationship between frailty or multimorbidity and MACE, hypoglycaemia, and falls.

This figure shows the predicted 5-year rate of fall or fracture (panels a, b, c, and d showing the frailty index, frailty phenotype, Charlson index, and long-term condition count, respectively) hospitalization with hypoglycaemia (panels e, f, g, and h showing the frailty index, frailty phenotype, Charlson index, and long-term condition count, respectively) and MACE (panels i, j, k and m showing the frailty index, frailty phenotype, Charlson index, and long-term condition count, respectively). Coloured lines or points indicate point estimates for predicted 5-year mortality. Men are shown in blue, and women in red. Shaded areas indicate 95% confidence intervals. Models are adjusted for age, sex, socioeconomic status, body mass index, smoking, and alcohol. Predicted 5-year risk is based on age 60, socioeconomic status and body mass index held at the sample mean, previous smokers, and 1–4 times weekly alcohol intake.