Table 2 Estimated parameters for the SARS-CoV-2 viral dynamics model
Parameters | Symbol | Unit | Median of fixed effecta (SE) | Covariate effect per year of age (SE) | Covariate effect of vaccination statusb (SE) | Standard deviation of random effectc (SE) |
|---|---|---|---|---|---|---|
Maximum rate constant for viral replication | \(\gamma\) | day−1 | 4.25 (9.12) | - | - | 3.05 (1.89) |
Death rate of infected cells | \(\delta\) | day−1 | 0.67 (0.04) | - | 0.95 (0.14) | 0.48 (0.05) |
Rate constant for virus infection | \(\beta\) | (copies/mL)−1 day−1 | 8.03 × 10−7 (8.24 × 10−7) | −0.05 (0.02) | −1.81 (1.03) | 0.77 (0.57) |
Viral load at symptom onset | \(V(0)\) | log10(copies/mL) | 8.98 × 107 (4.64 × 107) | - | 1.26 (0.96) | 2.29 (0.61) |
