Extended Data Fig. 9: PhIP-Seq analysis of patient-specific antigen targets. | Nature Cardiovascular Research

Extended Data Fig. 9: PhIP-Seq analysis of patient-specific antigen targets.

From: An engineered human cardiac tissue model reveals contributions of systemic lupus erythematosus autoantibodies to myocardial injury

Extended Data Fig. 9

(a) Table summarizing Pearson’s R quantified by correlation between different RO52 peptides measured by PhIP-Seq and clinical laboratory measurements of patient anti-Ro/SSA antibodies by ELISA. (b) Hierarchical clustering of peptides increased in Myo+SD+ patients compared to Myo- and Myo+SD- patients. Each column represents a patient (green; Myo- patients, blue; Myo+SD+ patients pink; Myo+SD+ patients). Each row represents a peptide identified by PhIP-Seq. (c) Schematic of surface protein analysis pipeline and filtering of identified proteins.

Back to article page