Surface engineering enhances the pharmacokinetics and pharmacodynamics of extracellular vesicles (EVs) by improving their stability, immune evasion, tracking and targeting. Advancing scalable chemical approaches that preserve the integrity and functionality of EVs and efficient purification methods are key to unlocking their full potential.
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Pourtalebi Jahromi, L., Fuhrmann, G. A chemical toolbox for surface engineering of extracellular vesicles. Nat Rev Bioeng (2025). https://doi.org/10.1038/s44222-025-00310-9
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DOI: https://doi.org/10.1038/s44222-025-00310-9
