Fig. 4: Plasma pharmacokinetics of FAPI reagents in healthy male DBA1/J mice following an IV bolus. | npj Imaging

Fig. 4: Plasma pharmacokinetics of FAPI reagents in healthy male DBA1/J mice following an IV bolus.

From: Increased imaging ligand hydrophilicity and improved pharmacokinetic properties provides enhanced in vivo targeting of fibroblast activation protein

Fig. 4

†Due to an expectation of rapid clearance, FAPI was dosed in ~25-fold molar excess of other conjugates to maintain plasma concentrations above lower limit of quantification (LLOQ) throughout sampling period. Concentrations plotted have been linearly dose adjusted for comparison to all other probes dosed at 2 nmol.

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