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Showing 1–6 of 6 results
Advanced filters: Author: Jacob Halatek Clear advanced filters

  • In the C. elegans zygote, (anterior) aPAR and (posterior) pPAR proteins are key to polarity maintenance, what factors determine the selection of the polarity axis remains unclear. Here authors formulate a reaction-diffusion model in realistic cell geometry and find that long-axis polarisation is promoted by cytosolic dephosphorylation at onset and its steady state determined by minimising the length of the aPAR-pPAR interface.

    • Raphaela Geßele
    • Jacob Halatek
    • Erwin Frey
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12

  • Self-organisation of Min protein patterns observed in vivo and in vitro differ qualitatively and quantitatively. Here the authors reconstituted Min proteins in laterally wide microchambers with a well-controlled height and show that the Min protein dynamics on the membrane crucially depend on the micro chamber height.

    • Fridtjof Brauns
    • Grzegorz Pawlik
    • Cees Dekker
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-11

  • Morphogen gradients can be dynamic and transient yet give rise to stable cellular patterns. Here the authors show that a synthetic morphogen-induced mutual inhibition circuit produces stable boundaries when the spatial average of morphogens falls within the region of bistability.

    • Paul K. Grant
    • Gregory Szep
    • Andrew Phillips
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-8

  • Meindlhumer et al. report a combined theoretical/experimental study of how the propagation direction of Min protein patterns can be altered by a bulk flow of solution.

    • Sabrina Meindlhumer
    • Fridtjof Brauns
    • Erwin Frey
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-10