Nature Search

What the little birds tell us

Jeremy J. D. Greenwood
News & Views04 Jan 1990
Nature

Volume: 343, P: 22-23
Cultured human endothelial cells express platelet-derived growth factor B chain: cDNA cloning and structural analysis

Tucker Collins
David Ginsburg
Jordan S. Pober
Research22 Aug 1985
Nature

Volume: 316, P: 748-750
Dynein in the spindle?

Jeremy Hyams
News & Views25 Feb 1982
Nature

Volume: 295, P: 648-649
Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism

Mark W. Sornson
Wei Wu
Michael G. Rosenfeld
Research28 Nov 1996
Nature

Volume: 384, P: 327-333
Proteomic analysis of cardiorespiratory fitness for prediction of mortality and multisystem disease risks

A proteomic risk score for cardiorespiratory fitness, comprising as few as 21 proteins, is dynamic with exercise training and helps predict the risk of mortality and a range of cardiovascular, metabolic and neurological conditions.

Andrew S. Perry
Eric Farber-Eger
Ravi V. Shah
ResearchOpen Access04 Jun 2024
Nature Medicine

Volume: 30, P: 1711-1721
Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals

Most studies of the genetics of the metabolome have been done in individuals of European descent. Here, the authors integrate genomics and metabolomics in Black individuals, highlighting the value of whole genome sequencing in diverse populations and linking circulating metabolites to human disease.

Usman A. Tahir
Daniel H. Katz
Robert E. Gerszten
ResearchOpen Access22 Aug 2022
Nature Communications

Volume: 13, P: 1-16
Evolutionary plasticity of the NHL ___domain underlies distinct solutions to RNA recognition

The C. elegans LIN-41 and its homologs, including human TRIM71/LIN41, contain the RNA binding NHL ___domain. Here the authors combine computational analysis, structural biology and in vivo studies, to explain how these proteins bind RNA and how rapid evolution of NHL domains resulted in different solutions to RNA recognition.

Pooja Kumari
Florian Aeschimann
Rafal Ciosk
ResearchOpen Access19 Apr 2018
Nature Communications

Volume: 9, P: 1-15
Structural insights into HDAC6 tubulin deacetylation and its selective inhibition

X-ray crystallographic analysis reveals features of the tandem catalytic domains of histone deacetylase 6 (HDAC6), their inhibition by small molecules and functional insights into the enzyme's role in tubulin deacetylation.

Yasuyuki Miyake
Jeremy J Keusch
Patrick Matthias
Research25 Jul 2016
Nature Chemical Biology

Volume: 12, P: 748-754
Author Correction: Human plasma proteomic profiles indicative of cardiorespiratory fitness

Jeremy M. Robbins
Bennet Peterson
Robert E. Gerszten
Amendments and Corrections27 Aug 2021
Nature Metabolism

Volume: 3, P: 1275
Genomic insights into the historical and contemporary demographics of the grey reef shark

Cameron A. J. Walsh
Paolo Momigliano
Stéphanie Manel
Research16 Mar 2022
Heredity

Volume: 128, P: 225-235
Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Dimethyl fumarate (DMF) is an anti-inflammatory drug proposed as a treatment for COVID19. Here the results are reported from a randomised trial testing DMF treatment in 713 patients hospitalised with COVID-19. DMF was not associated with any improvement in day 5 outcomes.

Peter Sandercock
Janet Darbyshire
Martin J. Landray
ResearchOpen Access31 Jan 2024
Nature Communications

Volume: 15, P: 1-13
Temporal dynamics of the multi-omic response to endurance exercise training

Temporal multi-omic analysis of tissues from rats undergoing up to eight weeks of endurance exercise training reveals widespread shared, tissue-specific and sex-specific changes, including immune, metabolic, stress response and mitochondrial pathways.

David Amar
Nicole R. Gay
Elena Volpi
ResearchOpen Access01 May 2024
Nature

Volume: 629, P: 174-183
Reply to ‘Lactate as a major myokine and exerkine’

Lisa S. Chow
Robert E. Gerszten
Michael Snyder
Correspondence01 Aug 2022
Nature Reviews Endocrinology

Volume: 18, P: 713
Human plasma proteomic profiles indicative of cardiorespiratory fitness

Plasma proteomic profiles from 650 adult humans are measured before and after a 20-week exercise regimen to determine proteins associated with baseline cardiorespiratory fitness and improvements in response to exercise.

Jeremy M. Robbins
Bennet Peterson
Robert E. Gerszten
Research27 May 2021
Nature Metabolism

Volume: 3, P: 786-797
The impact of exercise on gene regulation in association with complex trait genetics

It is known that exercise influences many human traits, but not which tissues and genes are most important. This study connects transcriptome data collected across 15 tissues during exercise training in rats as part of the Molecular Transducers of Physical Activity Consortium with human data to identify traits with similar tissue specific gene expression signatures to exercise.

Nikolai G. Vetr
Nicole R. Gay
Stephen B. Montgomery
ResearchOpen Access01 May 2024
Nature Communications

Volume: 15, P: 1-14
Muscle-derived stem/progenitor cell dysfunction limits healthspan and lifespan in a murine progeria model

The function of adult stem cells is diminished with age but the role this dysfunction plays in the aging process is unknown. Here, the injection of muscle-derived stem/progenitor cells from young mice rescues symptoms in progeroid mice and is shown to regenerate tissues independent of engraftment.

Mitra Lavasani
Andria R. Robinson
Johnny Huard
ResearchOpen Access03 Jan 2012
Nature Communications

Volume: 3, P: 1-12
Influenza virus uses transportin 1 for vRNP debundling during cell entry

A member of the importin-β protein family, transportin 1, binds to influenza A virus matrix protein M1 and promotes its removal from the viral ribonucleoproteins (vRNPs), enabling disassembly of vRNP bundles, vRNP interaction with importin-α/β and entry into the nucleus.

Yasuyuki Miyake
Jeremy J. Keusch
Yohei Yamauchi
Research28 Jan 2019
Nature Microbiology

Volume: 4, P: 578-586
Patient-derived mutations within the N-terminal domains of p85α impact PTEN or Rab5 binding and regulation

Paul Mellor
Jeremy D. S. Marshall
Deborah H. Anderson
ResearchOpen Access08 May 2018
Scientific Reports

Volume: 8, P: 1-13
36-month durability of ultrasound renal denervation for hypertension resistant to combination therapy in RADIANCE-HTN TRIO

Michael J. Bloch
Ajay J. Kirtane
Patric Kröpil
ResearchOpen Access27 Sept 2024
Hypertension Research

Volume: 47, P: 3467-3472
Tolerance of high levels of wild-type p53 in transformed epithelial cells dependent on auto-regulation by mdm-2

Jeremy P Blaydes
Véronique Gire
David Wynford-Thomas
Research17 Apr 1997
Oncogene

Volume: 14, P: 1859-1868
Interferon α2b gene delivery using adenoviral vector causes inhibition of tumor growth in xenograft models from a variety of cancers

C M Iqbal Ahmed
Duane E Johnson
Barry J Sugarman
Research30 Oct 2001
Cancer Gene Therapy

Volume: 8, P: 788-795
Exerkines in health, resilience and disease

Exerkines are signalling moieties that are released in response to acute and/or chronic exercise that exert their effects through endocrine, paracrine and/or autocrine pathways. This Review summarizes the importance and current state of exerkine research, prevailing challenges and future directions.

Lisa S. Chow
Robert E. Gerszten
Michael P. Snyder
Reviews18 Mar 2022
Nature Reviews Endocrinology

Volume: 18, P: 273-289
Author Correction: Supporting US public health experts

Ron Cohen
Cedric Francois
Sandy Zweifach
Amendments and Corrections17 Dec 2020
Nature Biotechnology

Volume: 39, P: 115
Pharmacologic IKK/NF-κB inhibition causes antigen presenting cells to undergo TNFα dependent ROS-mediated programmed cell death

Jeremy S. Tilstra
Daniel F. Gaddy
Paul D. Robbins
ResearchOpen Access10 Jan 2014
Scientific Reports

Volume: 4, P: 1-11
Supporting US public health experts

Ron Cohen
Cedric Francois
Sandy Zweifach
Correspondence25 Nov 2020
Nature Biotechnology

Volume: 38, P: 1381-1384
Effect of Variation in Diacylglycerol Kinase Eta (DGKH) Gene on Brain Function in a Cohort at Familial Risk of Bipolar Disorder

Heather C Whalley
Martina Papmeyer
Andrew M McIntosh
Research02 Nov 2011
Neuropsychopharmacology

Volume: 37, P: 919-928
Genomics and transcriptomics landscapes associated to changes in insulin sensitivity in response to endurance exercise training

Louise Y. Takeshita
Peter K. Davidsen
Francesco Falciani
ResearchOpen Access02 Dec 2021
Scientific Reports

Volume: 11, P: 1-14
A candidate tumor suppressor HtrA1 is downregulated in ovarian cancer

Jeremy Chien
Julie Staub
Viji Shridhar
Research05 Jan 2004
Oncogene

Volume: 23, P: 1636-1644
Recent expansion of marine protected areas matches with home range of grey reef sharks

Lucas Bonnin
David Mouillot
Laurent Vigliola
ResearchOpen Access09 Jul 2021
Scientific Reports

Volume: 11, P: 1-11
Whole-colon investigation vs. flexible sigmoidoscopy for suspected colorectal cancer based on presenting symptoms and signs: a multicentre cohort study

Amanda J. Cross
Kate Wooldrage
Wendy Atkin
ResearchOpen Access19 Dec 2018
British Journal of Cancer

Volume: 120, P: 154-164
Multiomics analysis of serial PARP inhibitor treated metastatic TNBC inform on rational combination therapies

Marilyne Labrie
Allen Li
Zahi I. Mitri
ResearchOpen Access19 Oct 2021
npj Precision Oncology

Volume: 5, P: 1-11
Adolescent Alcohol Exposure Amplifies the Incentive Value of Reward-Predictive Cues Through Potentiation of Phasic Dopamine Signaling

Marcia Spoelder
Kimberly T Tsutsui
Jeremy J Clark
Research14 May 2015
Neuropsychopharmacology

Volume: 40, P: 2873-2885
An Animal Model of Genetic Vulnerability to Behavioral Disinhibition and Responsiveness to Reward-Related Cues: Implications for Addiction

Shelly B Flagel
Terry E Robinson
Huda Akil
Research30 Sept 2009
Neuropsychopharmacology

Volume: 35, P: 388-400
Injectable Phosphorescence-based Oxygen Biosensors Identify Post Ischemic Reactive Hyperoxia

Jennifer S. Chien
Mahmoud Mohammed
Bruce Klitzman
ResearchOpen Access15 Aug 2017
Scientific Reports

Volume: 7, P: 1-10
Four consecutive yearly point-prevalence studies in Wales indicate lack of improvement in sepsis care on the wards

Maja Kopczynska
Harry Unwin
Judith E. Hall
ResearchOpen Access10 Aug 2021
Scientific Reports

Volume: 11, P: 1-12

Search

What the little birds tell us

Cultured human endothelial cells express platelet-derived growth factor B chain: cDNA cloning and structural analysis

Dynein in the spindle?

Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism

Proteomic analysis of cardiorespiratory fitness for prediction of mortality and multisystem disease risks

Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals

Evolutionary plasticity of the NHL ___domain underlies distinct solutions to RNA recognition

Structural insights into HDAC6 tubulin deacetylation and its selective inhibition

Author Correction: Human plasma proteomic profiles indicative of cardiorespiratory fitness

Genomic insights into the historical and contemporary demographics of the grey reef shark

Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Temporal dynamics of the multi-omic response to endurance exercise training

Reply to ‘Lactate as a major myokine and exerkine’

Human plasma proteomic profiles indicative of cardiorespiratory fitness

The impact of exercise on gene regulation in association with complex trait genetics

Muscle-derived stem/progenitor cell dysfunction limits healthspan and lifespan in a murine progeria model

Influenza virus uses transportin 1 for vRNP debundling during cell entry

Patient-derived mutations within the N-terminal domains of p85α impact PTEN or Rab5 binding and regulation

36-month durability of ultrasound renal denervation for hypertension resistant to combination therapy in RADIANCE-HTN TRIO

Tolerance of high levels of wild-type p53 in transformed epithelial cells dependent on auto-regulation by mdm-2

Interferon α2b gene delivery using adenoviral vector causes inhibition of tumor growth in xenograft models from a variety of cancers

Exerkines in health, resilience and disease

Author Correction: Supporting US public health experts

Pharmacologic IKK/NF-κB inhibition causes antigen presenting cells to undergo TNFα dependent ROS-mediated programmed cell death

Supporting US public health experts

Effect of Variation in Diacylglycerol Kinase Eta (DGKH) Gene on Brain Function in a Cohort at Familial Risk of Bipolar Disorder

Genomics and transcriptomics landscapes associated to changes in insulin sensitivity in response to endurance exercise training

A candidate tumor suppressor HtrA1 is downregulated in ovarian cancer

Recent expansion of marine protected areas matches with home range of grey reef sharks

Whole-colon investigation vs. flexible sigmoidoscopy for suspected colorectal cancer based on presenting symptoms and signs: a multicentre cohort study

Multiomics analysis of serial PARP inhibitor treated metastatic TNBC inform on rational combination therapies

Adolescent Alcohol Exposure Amplifies the Incentive Value of Reward-Predictive Cues Through Potentiation of Phasic Dopamine Signaling

An Animal Model of Genetic Vulnerability to Behavioral Disinhibition and Responsiveness to Reward-Related Cues: Implications for Addiction

Injectable Phosphorescence-based Oxygen Biosensors Identify Post Ischemic Reactive Hyperoxia

Four consecutive yearly point-prevalence studies in Wales indicate lack of improvement in sepsis care on the wards

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