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Showing 1–8 of 8 results

Advanced filters: Author: Jonathan D. Gilthorpe Clear advanced filters

The scaffolding function of LSD1 controls DNA methylation in mouse ESCs

This study suggests a mechanism by which LSD1 controls DNA methylation in mouse ESCs, independently of its lysine demethylase activity. The demethylase-independent function of LSD1 regulates the DNMT1 and UHRF1 protein stability through interaction with USP7 and HDAC1.

Sandhya Malla
Kanchan Kumari
Francesca Aguilo
ResearchOpen Access05 Sept 2024
Nature Communications

Volume: 15, P: 1-24
Dissecting the genetic landscape of GPCR signaling through phenotypic profiling in C. elegans

To overcome challenges posted by vast number of GPCR genes and redundancy, the authors disrupted nearly all GPCR-encoding genes in C. elegans, enabling effective examination of GPCR signaling and offering a valuable resource for the research community.

Longjun Pu
Jing Wang
Changchun Chen
ResearchOpen Access18 Dec 2023
Nature Communications

Volume: 14, P: 1-16
CAM-Delam: an in vivo approach to visualize and quantify the delamination and invasion capacity of human cancer cells

Tamilarasan K. Palaniappan
Lina Šlekienė
Lena Gunhaga
ResearchOpen Access26 Jun 2020
Scientific Reports

Volume: 10, P: 1-11
Publisher Correction: Altered perivascular fibroblast activity precedes ALS disease onset

Anna Månberg
Nathan Skene
Sebastian A. Lewandowski
Amendments and Corrections02 Jun 2021
Nature Medicine

Volume: 27, P: 1308
Altered perivascular fibroblast activity precedes ALS disease onset

Increased perivascular fibroblast activity and vascular remodeling occurs early in ALS pathogenesis and can predict patient survival time

Anna Månberg
Nathan Skene
Sebastian A. Lewandowski
Research15 Apr 2021
Nature Medicine

Volume: 27, P: 640-646
Role of pannexin-1 in the cellular uptake, release and hydrolysis of anandamide by T84 colon cancer cells

Mireille Alhouayek
René Sorti
Christopher J. Fowler
ResearchOpen Access20 May 2019
Scientific Reports

Volume: 9, P: 1-12
Mitochondrial DNA in the tumour microenvironment activates neutrophils and is associated with worse outcomes in patients with advanced epithelial ovarian cancer

Kelly L. Singel
Kassondra S. Grzankowski
Brahm H. Segal
ResearchOpen Access06 Dec 2018
British Journal of Cancer

Volume: 120, P: 207-217
Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis

Bastien Paré
Manuela Lehmann
François Gros-Louis
ResearchOpen Access21 Sept 2018
Scientific Reports

Volume: 8, P: 1-13