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Electroreduction of low-concentration NO₃⁻ to NH₃ is limited by NO₃⁻ mass transfer. Here, the authors propose a strategy for NO₃ ⁻ enrichment through charge rearrangement within the inner Helmholtz plane, achieving near-unity conversion of NO₃⁻ to NH₃.

A suite of bridged rhodamine dyes (BriDyes) offers excellent brightness, solubility, photostability, and tunable cell permeability along with resistance to photoblueing, making them exceptional all-purpose dyes for fluorescence biomaging.

Silicon electrodes promise high energy for lithium-ion batteries but face swelling and durability issues. Here, the authors develop a sieving-pore design that enables stable, fast-charging silicon electrodes with long cycle life, low expansion, and industrial-scale potential.

The authors present a feasible strategy of anion-induced strain engineering to regulate the lattice structure and properties of super-elongated BiFeO₃ epitaxial films, revealing the correlations among lattice distortion, local electronic hybridization, and multiferroic properties.

Spin-split bands and certain lattice symmetries are required to generate the spin currents needed for spintronics applications. Now a layered room-temperature antiferromagnet is shown to exhibit anisotropic spin splitting between valleys paired by a crystal symmetry.

Current-driven dynamic atomic rearrangements in layered In₂Se₃ are visualized. The authors identify an intralayer ‘unzipping’ and interlayer ‘zipping’ phase-transition pathway in which bond formation across the van der Waals gaps drives bond cleavage within covalent layers.

Skyrmions are objects with whirled magnetization protected by their topology that can be created by different means, however, without control of their position. Here, the authors present a method exploiting x-rays to create skyrmions at the beam position allowing for creation of artificial skyrmion lattices.

Material implementation of machine learning algorithms for advanced computing at cryogenic temperature remains rare. Here, the authors report a cryogenic in-memory computing platform using chiral edge states of magnetic topological insulators.

Strong magnetic interfacial coupling in van der Waals heterostructures provides a new platform for discovering novel physics and effects. Here, the authors report the formation of skyrmion lattice in the WTe₂/Fe₃GeTe₂ van der Waals heterostructure and a Dzyaloshinskii–Moriya interaction with a large energy density of 1.0 mJm⁻².

Single atom catalysts offer a promising approach for CO₂ electroreduction to CO, but achieving high efficiency remains challenging. Here, the authors report lanthanide single atom catalysts with the transition ability from bridge to linear adsorption that exhibit efficient CO production.

There is a long-standing trade-off between piezoelectric coefficient and mechanical quality factor for piezoceramics. Here, authors embed local defect dipoles into phase boundary engineering to relieve this relationship in (K, Na) NbO3 piezoceramics.

Dirac semimetals have been proposed as parent materials for other topologically non-trivial phases such as Weyl semimetals, achieved by the breaking of time reversal symmetry. Here the authors use transport measurements to evidence such behaviour in single crystal Cd₃As₂under an applied magnetic field.

Deuterated molecules are important both as labelled probes and as targets in their own right. Here the authors report a very simple and general deuteration of aldehydes, by the use of an N-heterocyclic carbene catalyst in the presence of D₂O.

Depression has been recently linked to the visual cortex. Here, the authors identify a glutamatergic primary visual corticallateral posterior thalamic nucleus circuit and its key regulator, Gγ4, as modulators of depressive-like behaviors in male mice.

Diabetes-associated cognitive dysfunction (DACD) is increasingly recognized as a critical complication of diabetes. Here, the authors show that SGK1 drives hippocampal demyelination and DACD via regulating NDRG1 phosphorylation.

There are now several van der Waals magnets that have been shown to host skyrmions, however, these are typically hampered by a low Curie temperature, restricting the temperature at which the skyrmions can exist. Here, Zhang, Jiang, Jiang and coauthors find a skyrmion lattice in the van der Waals magnet Fe3 − xGaTe2 above room temperature and demonstrate the critical role of symmetry breaking in crystal lattice in the origin of these skyrmions.

He et al. report spin-LEDs based on chiral perovskite quantum dots which act as localized spin-selective units and radiative recombination centers simultaneously. Ultrasonic treatment assisted ligand exchange enables spin-LEDs with peak efficiency of 16.8% and dissymmetry factor of 0.285.

Aqueous sulfur-based redox flow batteries (SRFBs) are promising candidates for large-scale energy storage, yet the gap between the required and currently achievable performance has plagued their practical applications. Here, we propose several engineering strategies towards SRFB commercialization.

Genetically encoded dense core vesicle markers, compatible with immunohistochemistry and expansion microscopy, enable single-vesicle resolution in Drosophila using confocal microscopy.

Most photonic processors can only handle a single data modality due to the lack of abundant parameter training in optical ___domain. Here, authors propose and demonstrate a trainable diffractive optical neural network chip based on on-chip diffractive optics with tunable elements to address these constraints.

Comparative genomics can provide valuable insights on adaptations to hostile environments. Here, the authors sequence the genomes and transcriptomes of the Bactrian camel, dromedary and alpaca, to reveal the demographic history of the group as well as metabolic adaptations to the desert environment.

Nucleoli are essential cellular sites for ribosome biogenesis that are formed by liquid-liquid phase separation. Here the authors show that METTL3/METTL14 maintain nucleoli integrity through mediating SUV39H1/2 degradation in human embryonic stem cells.

Aluminum-ion batteries require stable and efficient cathodes for reversible Al-complex ion insertion. Here, an TiNbCTx MXene is used as a cathode, achieving reversible capacity of 194 mAh·g⁻¹ at 0.2 A·g⁻¹, with 800-cycle stability.

Here the authors show that lithium carbonate can revitalize tumor-reactive CD8⁺T cells by shunting cytosolic lactic acid into the mitochondria for oxidation, indicating that lithium ions might be applied as a cancer immunotherapy.

This study reveals functional heterogeneity at the level of exocytosis among β cells and identifies a subpopulation of β cells that make a disproportionally large contribution to insulin release from mouse islets.

The magnetic anisotropy of the van der Waals ferromagnet Fe₅GeTe₂ can be continuously tuned—from an initial out-of-plane orientation to a canted orientation and then finally to an in-plane orientation—using electrical gating.

Antibodies against SARS-CoV-2 S protein can provide a treatment strategy for COVID-19. Here, Guo et al. provide the crystal structure of a SARS-CoV2 neutralizing antibody isolated from a convalescent patient and highlight the therapeutic efficacy in a rhesus monkey model of an engineered version with optimized pharmacokinetic and safety profile.

The spatial organisation of diffuse midline glioma-H3K27M mutant (DMG) and glioblastoma (GBM) remains to be investigated. Here, the authors integrate short-read and long-read spatial profiling of DMG and GBM to identify regulatory programs and cellular ecosystems in distinct glioma niches.

In Bi₂O₂Se thin films, the local inversion-symmetry breaking in two sectors of the [Bi₂O₂]²⁺ layer yields opposite Rashba spin polarizations, which compensate each other and give rise to the hidden Rashba effect. Hence, the films exhibit only even-integer quantum Hall states, but there is no sign of odd-integer states.

Current contrast-enhanced magnetic resonance angiography approaches are sub-optimal. Here the authors present a hypersensitive MR angiography strategy based on interlocking stratagem of zwitterionic Gd-chelate contrast agents (PAA-Gd), enabling sophisticated micro-vessel angiography of cardiac-cerebrovascular diseases with ultrahigh resolution.

Lampreys, an ancient vertebrate lineage, can provide unique insights into early retinal evolution. Using scRNA-seq and computational analysis, this study compared retinal cell types between lamprey and jawed species, illuminating retinal cell origins and diversification.

Fluctuation of the cation valence state plays a crucial role in emergent quantum phenomena in correlated electron systems. Here, the authors demonstrate a valence-fluctuation-driven insulator-to-superconductor transition in the van der Waals insulator GeP as a function of hydrostatic pressure.

Superionic fluoride dielectrics with a low ion migration barrier are capable of excellent capacitive coupling and are highly compatible with scalable device manufacturing processes for integrated electronics.

Whole-genome sequencing of 175 Mongolians representing six tribes highlights population-specific genetic architecture and substantial gene flow among northern Eurasian populations, including derived alleles shared by Mongolians and Finns.

The excessive porous space in carbon anodes for lithium-ion batteries has to be utilized for high volumetric performance. Here the authors show an adaptable sulfur template strategy to yield graphene-caged noncarbon materials with a precisely controlled amount of void, enabling ultrahigh volumetric lithium storage.