In this study, we designed an injectable antibacterial hydrogel that was photopolymerized by visible light for the treatment of skin infections. The hydrogel consists of γ-poly(glutamic acid)-glycidyl methacrylate (γ-PGA-GMA) and ε-polylysine-glycidyl methacrylate (ε-PL-GMA). The hydrogels showed the characteristics of injectable and rapid gels, and were easy to use. Importantly, the hydrogels demonstrated high levels of antibacterial activity and biocompatibility. In in vivo infection models, the hydrogels reduced inflammation, promoted wound healing, and shortened the healing time. This highlights the hydrogels as promising candidates for anti-infection and wound healing.
- Ao Sun
- Xinye He
- Zhiyong Qian
