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Advanced filters: Author: Pingfeng Zhang Clear advanced filters

Structural insights into the transporting and catalyzing mechanism of DltB in LTA D-alanylation

Here, the authors structurally and functionally characterise DltB, a member of the Membrane-Bound O-AcylTransferase (MBOAT) superfamily responsible for D-alanine incorporation in the cell wall of gram-positive bacteria.

Pingfeng Zhang
Zheng Liu
ResearchOpen Access22 Apr 2024
Nature Communications

Volume: 15, P: 1-12
Direct stimulation of de novo nucleotide synthesis by O-GlcNAcylation

Phosphoribosyl pyrophosphate synthetase (PRPS1), an enzyme that regulates de novo nucleotide synthesis, was found to be O-GlcNAcylated, which increases PRPS1 activity, and is associated with increased tumorigenesis and resistance to chemoradiotherapy.

Lulu Chen
Qi Zhou
Huadong Pei
ResearchOpen Access12 Jun 2023
Nature Chemical Biology

Volume: 20, P: 19-29
Multilevel thresholding with divergence measure and improved particle swarm optimization algorithm for crack image segmentation

Fangyan Nie
Mengzhu Liu
Pingfeng Zhang
ResearchOpen Access01 Apr 2024
Scientific Reports

Volume: 14, P: 1-19