Nature Search

Publisher Correction: Inhibition of fatty acid oxidation enables heart regeneration in adult mice

Xiang Li
Fan Wu
Thomas Braun
Amendments and CorrectionsOpen Access20 Oct 2023
Nature

Volume: 623, P: E7
Inhibition of fatty acid oxidation enables heart regeneration in adult mice

Inhibition of the fatty acid oxidation metabolic pathway through inactivation of Cpt1b enhances cardiomyocyte survival and proliferation and allows heart regeneration in adult mice.

Xiang Li
Fan Wu
Thomas Braun
ResearchOpen Access27 Sept 2023
Nature

Volume: 622, P: 619-626
Calcium bursts allow rapid reorganization of EFhD2/Swip-1 cross-linked actin networks in epithelial wound closure

Calcium serves as an important second messenger in signal transduction to the actin cytoskeleton. Here, we identify EFhD2/Swip-1 as a calcium-dependent actin cross-linker promoting rapid reorganization of actin networks in epithelial wound closure.

Franziska Lehne
Thomas Pokrant
Sven Bogdan
ResearchOpen Access06 May 2022
Nature Communications

Volume: 13, P: 1-17
G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators

P2Y10 is a G-protein-coupled receptor that is expressed in CD4 T cells. Here authors show that its ligands, lysophosphatidylserine and ATP, are induced in T cells upon chemokine stimulation and regulate RhoA activation and migration through an autocrine/paracrine loop.

Malarvizhi Gurusamy
Denise Tischner
Nina Wettschureck
ResearchOpen Access23 Nov 2021
Nature Communications

Volume: 12, P: 1-16
Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program

Ascl1 and Sox2 convert human brain pericytes into the two major neuronal subclasses of GABA- and glutamatergic neurons. Unexpectedly, despite the lack of cell division, this conversion requires passage through a neural stem cell-like state.

Marisa Karow
J. Gray Camp
Benedikt Berninger
Research18 Jun 2018
Nature Neuroscience

Volume: 21, P: 932-940
Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells

During atherosclerosis, endothelial cells release purines in response to oxidized phospholipids. Here, Hitzel et al. show that oxidized phospholipids activate an MTHFD2-regulated gene network in endothelial cells which reprograms amino acid metabolism towards production of purines and thus compensates for their loss.

Juliane Hitzel
Eunjee Lee
Ralf P. Brandes
ResearchOpen Access12 Jun 2018
Nature Communications

Volume: 9, P: 1-18
Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy

A product of the soluble epoxide hydrolase enzyme, 19,20-dihydroxydocosapentaenoic acid (19,20-DHDP), is implicated in the pathogenesis of diabetic retinopathy; levels of 19,20-DHDP increase in the retinas of mice and humans with diabetes, and inhibition of its production can rescue vascular abnormalities in a mouse model of the disease.

Jiong Hu
Sarah Dziumbla
Ingrid Fleming
Research06 Dec 2017
Nature

Volume: 552, P: 248-252
A transient increase of HIF-1α during the G1 phase (G1-HIF) ensures cell survival under nutritional stress

Ratnal Belapurkar
Maximilian Pfisterer
M. Lienhard SCHMITZ
ResearchOpen Access27 Jul 2023
Cell Death & Disease

Volume: 14, P: 1-15
UBTF tandem duplications are rare but recurrent alterations in adult AML and associated with younger age, myelodysplasia, and inferior outcome

Julia-Annabell Georgi
Sebastian Stasik
Christian Thiede
ResearchOpen Access26 May 2023
Blood Cancer Journal

Volume: 13, P: 1-8
Relation between platelet coagulant and vascular function, sex-specific analysis in adult survivors of childhood cancer compared to a population-based sample

Marina Panova-Noeva
Bianca Wagner
Philipp S. Wild
ResearchOpen Access27 Dec 2019
Scientific Reports

Volume: 9, P: 1-9
Galectin-3 for prediction of cardiac function compared to NT-proBNP in individuals with prediabetes and type 2 diabetes mellitus

Volker H. Schmitt
Jürgen H. Prochaska
Philipp S. Wild
ResearchOpen Access24 Sept 2021
Scientific Reports

Volume: 11, P: 1-12

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Publisher Correction: Inhibition of fatty acid oxidation enables heart regeneration in adult mice

Inhibition of fatty acid oxidation enables heart regeneration in adult mice

Calcium bursts allow rapid reorganization of EFhD2/Swip-1 cross-linked actin networks in epithelial wound closure

G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators

Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program

Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells

Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy

A transient increase of HIF-1α during the G1 phase (G1-HIF) ensures cell survival under nutritional stress

UBTF tandem duplications are rare but recurrent alterations in adult AML and associated with younger age, myelodysplasia, and inferior outcome

Relation between platelet coagulant and vascular function, sex-specific analysis in adult survivors of childhood cancer compared to a population-based sample

Galectin-3 for prediction of cardiac function compared to NT-proBNP in individuals with prediabetes and type 2 diabetes mellitus

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