The cellular uptake of polymeric nanoparticles composed of biodegradable amphiphilic polymers was observed by scanning electron microscopy employing an ionic liquid for the first time. In particular, these NPs were observed when the quantum dots were immobilized on the NPs. In addition, when the cells were incubated with microparticles, the filopodia that covered the MPs were observed, and the cellular uptake of the MPs was evaluated in a time-dependent manner.
- Fumiaki Shima
- Takami Akagi
- Mitsuru Akashi
