Imaging and sensing articles from across Nature Portfolio

Authors report an oblique photothermal microscope system for ultrasensitive infrared spectroscopic imaging of live subjects at sub-micron resolutions. The method enables low-dose skin imaging without photodamage, and is a highly sensitive platform for in vivo and in situ molecular analysis.

Label-free holo-tomographic flow cytometry enables 3D analysis of nuclei in suspended cells of acute myeloid leukemia, revealing a correlation between NPM1-mutations and cup-like morphology, potentially improving diagnostics with virtual reality integration.

A broadband achromatic metalens with high NA is demonstrated by a concept of stepwise phase dispersion compensation.

Local measurements of biological voltage production are key drivers of understanding in neurobiology and neurological and cardiac pathophysiology. Researchers have now shown that exciton–trion conversion in a two-dimensional semiconductor, MoS₂, can be used to optically image cardiomyocyte action-potentials in real-time.