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Showing 1–50 of 55 results

Advanced filters: Author: Shipra Clear advanced filters

Why it took me eight years and three postdoc jobs to describe myself as a scientist

Research and reading helped Shipra Jain to gain confidence in her abilities.

Shipra Jain
Comments & Opinion10 Mar 2020
Nature
Global, regional and national burden of dietary iron deficiency from 1990 to 2021: a Global Burden of Disease study

Systematic analysis from the Global Burden of Disease study reported that, despite global improvements from 1990 to 2021, dietary iron deficiency-associated disease burden remains high in women, children and residents in low socio-demographic index countries.

Sooji Lee
Yejun Son
Nicholas. J. Kassebaum
Research22 Apr 2025
Nature Medicine

Volume: 31, P: 1809-1829
Towards developing an operational Indian ocean dipole warning system for Southeast Asia

Shipra Jain
Thea Turkington
Theodore G. Shepherd
ResearchOpen Access27 Apr 2025
Scientific Reports

Volume: 15, P: 1-12
Erratum: Dyslipidaemia in nephrotic syndrome: mechanisms and treatment

Shipra Agrawal
Joshua J. Zaritsky
William E. Smoyer
Amendments and Corrections13 Dec 2017
Nature Reviews Nephrology

Volume: 14, P: 70
Computational Studies Of Huntington Protein: Classification & Binding Pattern Determination

Nitin Chitranshi
Shipra Gupta
MultimediaOpen Access24 Jan 2011
Nature Precedings

P: 1
Endowing universal CAR T-cell with immune-evasive properties using TALEN-gene editing

Host versus graft reaction is a major impediment to CAR-T cell immune therapy in allogeneic settings. Authors show here that CAR-T cells, engineered to be deficient in MHC I expression but to express the NK inhibitor HLA-E, are resistant to destruction by both T and NK cells of the host.

Sumin Jo
Shipra Das
Julien Valton
ResearchOpen Access30 Jun 2022
Nature Communications

Volume: 13, P: 1-16
The hyphal-specific toxin candidalysin promotes fungal gut commensalism

Both the yeast and hyphal forms of Candida albicans enable colonization of the mammalian gut, with hyphal cells secreting the toxin candidalysin to inihibit bacteria and support fungal commensalism.

Shen-Huan Liang
Shabnam Sircaik
Richard J. Bennett
Research06 Mar 2024
Nature

Volume: 627, P: 620-627
Windows of opportunity for predicting seasonal climate extremes highlighted by the Pakistan floods of 2022

This paper highlights the potential for improved monitoring and physical understanding to identify windows of opportunity for more confident seasonal forecasts and early warnings of regional climate extremes, such as the Pakistan floods of 2022.

Nick Dunstone
Doug M. Smith
Adam A. Scaife
ResearchOpen Access17 Oct 2023
Nature Communications

Volume: 14, P: 1-11
Single-molecule imaging with cell-derived nanovesicles reveals early binding dynamics at a cyclic nucleotide-gated ion channel

Here the authors use nanovesicles, microfluidics and single-molecule methods to observe individual ligand binding events that stimulate activation of CNG ion channels. They find that binding is followed by a conformational change of either independent or weakly cooperative binding domains.

Vishal R. Patel
Arturo M. Salinas
Marcel P. Goldschen-Ohm
ResearchOpen Access09 Nov 2021
Nature Communications

Volume: 12, P: 1-13
Increased renal elimination of endogenous and synthetic pyrimidine nucleosides in concentrative nucleoside transporter 1 deficient mice

Concentrative nucleoside transporters (CNTs) are cellular nucleoside influx systems, but their in vivo roles are poorly defined. By generating CNT1 knockout (KO) mice, here the authors show a role of CNT1 in the renal reabsorption of endogenous and synthetic nucleosides.

Avinash K. Persaud
Matthew C. Bernier
Rajgopal Govindarajan
ResearchOpen Access01 Jun 2023
Nature Communications

Volume: 14, P: 1-19
Network Walking charts transcriptional dynamics of nitrogen signaling by integrating validated and predicted genome-wide interactions

Temporal control of transcriptional networks enables organisms to adapt to changing environment. Here, the authors use a scaled-up cell-based assay to identify direct targets of nitrogen-early responsive transcription factors and validate a network path mediating dynamic nitrogen signaling in Arabidopsis.

Matthew D. Brooks
Jacopo Cirrone
Gloria M. Coruzzi
ResearchOpen Access05 Apr 2019
Nature Communications

Volume: 10, P: 1-13
AIntibody: an experimentally validated in silico antibody discovery design challenge

M. Frank Erasmus
Laura Spector
Andrew R. M. Bradbury
Correspondence04 Nov 2024
Nature Biotechnology

Volume: 42, P: 1637-1642
Cost-effective Whole Exome Sequencing discovers pathogenic variant causing Neurofibromatosis type 1 in a family from Jammu and Kashmir, India

Akshi Spolia
Arshia Angural
Ekta Rai
ResearchOpen Access15 May 2023
Scientific Reports

Volume: 13, P: 1-7
Parasite-induced T_H1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells

Immune responses can cause immunopathology. Yarovinsky and colleagues show that IFN-γ induced by T cell–intrinsic TLR signaling in CD4⁺ T_H1 cells during Toxoplasma gondii infection causes dysbiosis and loss of Paneth cells.

Megan Raetz
Sun-hee Hwang
Felix Yarovinsky
Research23 Dec 2012
Nature Immunology

Volume: 14, P: 136-142
ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss

Studies on a new conditional mouse model reveal that ETS transcription factors, which are often mutated in prostate cancer, cause transformation by altering the androgen-receptor cistrome, priming the prostate epithelium to respond to upstream signals such as PTEN loss.

Yu Chen
Ping Chi
Charles L Sawyers
Research30 Jun 2013
Nature Medicine

Volume: 19, P: 1023-1029
Left sided breast cancer is associated with aggressive biology and worse outcomes than right sided breast cancer

Yara Abdou
Medhavi Gupta
Kazuaki Takabe
ResearchOpen Access04 Aug 2022
Scientific Reports

Volume: 12, P: 1-9
Author Correction: Increased renal elimination of endogenous and synthetic pyrimidine nucleosides in concentrative nucleoside transporter 1 deficient mice

Avinash K. Persaud
Matthew C. Bernier
Rajgopal Govindarajan
Amendments and CorrectionsOpen Access07 Jun 2023
Nature Communications

Volume: 14, P: 1
Ozone therapy as a complementary approach in periodontal therapeutics

Shubham Sareen
Shipra Gupta
Lata Goyal
Comments & Opinion13 May 2025
Evidence-Based Dentistry

Volume: 26, P: 91-92
Effect of essential fatty acid blend on circadian variations of ambulatory blood pressure in patients with essential hypertension and coronary artery disease risk markers

Kshitij Bhardwaj
Narsingh Verma
Shipra Bhardwaj
Research23 Mar 2021
Journal of Human Hypertension

Volume: 36, P: 289-298
Structural basis for DNA 3′-end processing by human tyrosyl-DNA phosphodiesterase 1

Human tyrosyl-DNA phosphodiesterase 1 (Tdp1) repairs covalently trapped topoisomerase 1B-DNA complexes and other lesions, and is a target for anticancer drug development. Here the authors use an integrated structural approach to shed light onto the molecular basis of DNA end-processing by Tdp1.

Fiona J. Flett
Emilija Ruksenaite
Julia M. Richardson
ResearchOpen Access02 Jan 2018
Nature Communications

Volume: 9, P: 1-13
Fidelity of CMIP5 multi-model mean in assessing Indian monsoon simulations

Saroj K. Mishra
Sandeep Sahany
Shipra Jain
ResearchOpen Access22 Oct 2018
npj Climate and Atmospheric Science

Volume: 1, P: 1-8
Association between restoration of missing teeth with dentures and cognitive function

Lata Goyal
Komal Kaur Saroya
Shubham Sareen
Comments & Opinion09 May 2025
Evidence-Based Dentistry

Volume: 26, P: 85-86
The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation

The splicing factor SRSF1 is an oncoprotein that is upregulated in human tumors, including breast cancer tumors. New in vitro and in vivo analyses reveal SRSF1's ability to transform human mammary epithelial cells and promote mammary gland tumorigenesis in a mouse model by regulating apoptosis and proliferation and cooperating with Myc while also uncovering potential downstream therapeutic targets.

Olga Anczuków
Avi Z Rosenberg
Adrian R Krainer
Research15 Jan 2012
Nature Structural & Molecular Biology

Volume: 19, P: 220-228
Genome-wide association study of peripheral artery disease in the Million Veteran Program

A genome-wide association study using electronic health record data in the Million Veteran Program uncovers new genetic loci associated specifically with peripheral artery disease, as compared to stroke or coronary artery disease.

Derek Klarin
Julie Lynch
Scott M. Damrauer
Research08 Jul 2019
Nature Medicine

Volume: 25, P: 1274-1279
Nuclear receptors in podocyte biology and glomerular disease

Nuclear receptors have important roles in normal physiological functions and in the pathophysiology of various diseases. Here, the authors focus on the roles of nuclear receptors in podocyte biology and non-diabetic glomerular disease as well as their potential as therapeutic targets.

Shipra Agrawal
John C. He
Pierre-Louis Tharaux
Reviews17 Sept 2020
Nature Reviews Nephrology

Volume: 17, P: 185-204
Impact of concurrent diabetes on periodontal health in patients with acromegaly

Akanksha Jain
Shipra Gupta
Rose Kanwaljeet Kaur
ResearchOpen Access05 Nov 2020
Scientific Reports

Volume: 10, P: 1-8
Adsorption and DFT investigations of Cr(VI) removal using nanocrystals decorated with graphene oxide

Simranjeet Singh
Amith G. Anil
Praveen C. Ramamurthy
ResearchOpen Access13 Mar 2024
npj Clean Water

Volume: 7, P: 1-13
Dyslipidaemia in nephrotic syndrome: mechanisms and treatment

Dyslipidaemia is a common consequence of nephrotic syndrome, and results in various cardiovascular and metabolic complications. In this Review, the authors discuss the mechanisms that underlie the development of dyslipidaemia, and the treatment options that are available to ameliorate its effects.

Shipra Agrawal
Joshua J. Zaritsky
William E. Smoyer
Reviews27 Nov 2017
Nature Reviews Nephrology

Volume: 14, P: 57-70
A pigeonpea gene confers resistance to Asian soybean rust in soybean

Soybean is made resistant to Asian soybean rust using a gene cloned from pigeonpea, showing that legumes may contain a reservoir of disease-resistance genes.

Cintia G Kawashima
Gustavo Augusto Guimarães
Sérgio H Brommonschenkel
Research25 Apr 2016
Nature Biotechnology

Volume: 34, P: 661-665
Alternative transcription initiation leads to expression of a novel ALK isoform in cancer

A novel ALK transcript expressed in a subset of human cancers, arising from a de novo alternative transcription initiation site within the ALK gene, is described; the ALK transcript encodes three protein isoforms that stimulate tumorigenesis in vivo in mouse models; resultant tumours are sensitive to treatments with ALK inhibitors, indicating a possible therapeutic avenue for patients expressing these isoforms.

Thomas Wiesner
William Lee
Ping Chi
Research07 Oct 2015
Nature

Volume: 526, P: 453-457
Molecular determinants of epithelial mesenchymal transition in mouse placenta and trophoblast stem cell

Shipra Kanti Jena
Shreya Das
Rupasri Ain
ResearchOpen Access06 Jul 2023
Scientific Reports

Volume: 13, P: 1-15
Clinical outcomes of de novo metastatic HER2-low breast cancer: a National Cancer Database Analysis

Changchuan Jiang
Stuthi Perimbeti
Shipra Gandhi
ResearchOpen Access30 Dec 2022
npj Breast Cancer

Volume: 8, P: 1-9
Tooth vitality and periapical healing: is Biodentine at par with MTA in regenerative endodontics?

Shubham Sareen
Prabhleen Kaur Brar
Lata Goyal
Comments & Opinion31 Jan 2025
Evidence-Based Dentistry

Volume: 26, P: 6-7
Is periodontal disease associated with gestational diabetes? Exploring the evidence

Lata Goyal
Mehak Gupta
Shipra Gupta
Comments & Opinion31 Jan 2025
Evidence-Based Dentistry

Volume: 26, P: 52-53
Point biserial correlation symbiotic organism search nanoengineering based drug delivery for tumor diagnosis

Garima Shukla
Sofia Singh
Ben Othman Soufiene
ResearchOpen Access19 Mar 2024
Scientific Reports

Volume: 14, P: 1-19
Is saltwater mouth rinse as effective as chlorhexidine following periodontal surgery?

Shipra Gupta
Akanksha Jain
Mohita Singla
Reviews17 Dec 2021
Evidence-Based Dentistry

Volume: 22, P: 130-131
Pioglitazone Enhances the Beneficial Effects of Glucocorticoids in Experimental Nephrotic Syndrome

S. Agrawal
M. A. Chanley
W. E. Smoyer
ResearchOpen Access04 May 2016
Scientific Reports

Volume: 6, P: 1-9
BTK signaling drives CD1d^hiCD5⁺ regulatory B-cell differentiation to promote pancreatic carcinogenesis

Shipra Das
Dafna Bar-Sagi
Research11 Jan 2019
Oncogene

Volume: 38, P: 3316-3324
Early surgery in very preterm infants is associated with brain abnormalities on term MRI: a propensity score analysis

Katsuaki Kojima
Chunyan Liu
Nehal A. Parikh
Research25 Mar 2023
Journal of Perinatology

Volume: 43, P: 877-883
A systematic study of arsenic adsorption and removal from aqueous environments using novel graphene oxide functionalized UiO-66-NDC nanocomposites

Simranjeet Singh
T. S. Sunil Kumar Naik
Praveen C. Ramamurthy
ResearchOpen Access22 Sept 2022
Scientific Reports

Volume: 12, P: 1-15
Antibiotics as adjunct to non-surgical periodontal therapy in diabetic patients

Lata Goyal
Shipra Gupta
Yeshwanth Perambudhuru
Comments & Opinion15 Nov 2024
Evidence-Based Dentistry

Volume: 25, P: 202-203
Does the evidence support in utero influences on later health and disease? A systematic review of highly cited Barker studies on developmental origins

Shipra Jain
Lauren Samycia
Tanis R. Fenton
Reviews09 Feb 2024
Journal of Perinatology

Volume: 44, P: 1244-1251
UACA locus is associated with breast cancer chemoresistance and survival

Qianqian Zhu
Emily Schultz
Lawrence H. Kushi
ResearchOpen Access23 Mar 2022
npj Breast Cancer

Volume: 8, P: 1-12
Cardiovascular changes after pneumonia in a dual disease mouse model

Benjamin Bartlett
Herbert P. Ludewick
Girish Dwivedi
ResearchOpen Access01 Jul 2022
Scientific Reports

Volume: 12, P: 1-10
Identification of Novel Regulatory Genes in APAP Induced Hepatocyte Toxicity by a Genome-Wide CRISPR-Cas9 Screen

Katherine Shortt
Daniel P. Heruth
Shui Qing Ye
ResearchOpen Access04 Feb 2019
Scientific Reports

Volume: 9, P: 1-19
Space-like ⁵⁶Fe irradiation manifests mild, early sex-specific behavioral and neuropathological changes in wildtype and Alzheimer’s-like transgenic mice

Bin Liu
Robert G. Hinshaw
Cynthia A. Lemere
ResearchOpen Access20 Aug 2019
Scientific Reports

Volume: 9, P: 1-17
Lampreys, the jawless vertebrates, contain three Pax6 genes with distinct expression in eye, brain and pancreas

Vydianathan Ravi
Shipra Bhatia
Dirk A. Kleinjan
ResearchOpen Access20 Dec 2019
Scientific Reports

Volume: 9, P: 1-12
Physico-Chemical Condition Optimization during Biosynthesis lead to development of Improved and Catalytically Efficient Gold Nano Particles

Madhuree Kumari
Aradhana Mishra
Chandra Shekhar Nautiyal
ResearchOpen Access08 Jun 2016
Scientific Reports

Volume: 6, P: 1-14
The association between second-hand smoke and the periodontal status of children and adolescents

Vaibhav Sahni
Shipra Gupta
Reviews23 Sept 2022
Evidence-Based Dentistry

Volume: 23, P: 106-107
Do clinical decision support tools have a role to play in dealing with paediatric dental trauma?

Vaibhav Sahni
Shipra Gupta
Reviews24 Jun 2022
Evidence-Based Dentistry

Volume: 23, P: 74-75

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