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Showing 1–3 of 3 results
Advanced filters: Author: Aden Forrow Clear advanced filters

  • Lineage tracing and snapshots of transcriptional state at the single-cell level are powerful, complementary tools for studying development. Here, the authors propose a mathematical method combining lineage tracing with trajectory inference to improve our understanding of development.

    • Aden Forrow
    • Geoffrey Schiebinger
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-10

  • Lupu, Grainger, Kirschnick et al. show that, contrary to prevailing belief, the initial specification of mammalian lymphatic endothelial cells primarily occurs from previously unidentified mesenchymal angioblasts rather than from venous endothelium.

    • Irina-Elena Lupu
    • David E. Grainger
    • Oliver A. Stone
    ResearchOpen Access
    Nature Cardiovascular Research
    Volume: 4, P: 45-63

  • Reconstructing system dynamics on complex high-dimensional energy landscapes from static experimental snapshots remains challenging. Here, the authors introduce a framework to infer the essential dynamics of physical and biological systems without need for time-dependent measurements.

    • Philip Pearce
    • Francis G. Woodhouse
    • Jörn Dunkel
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-8