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Showing 1–4 of 4 results

Advanced filters: Author: Agusti Alentorn Clear advanced filters

Transcriptomic immune profiling of ovarian cancers in paraneoplastic cerebellar degeneration associated with anti-Yo antibodies

Clément Vialatte de Pémille
Giulia Berzero
Agusti Alentorn
ResearchOpen Access14 Jun 2018
British Journal of Cancer

Volume: 119, P: 105-113
Cellular senescence in malignant cells promotes tumor progression in mouse and patient Glioblastoma

Senescence can have beneficial and detrimental impact on cancer progression depending on the cellular context. Here the authors show that NRF2 regulates the senescence phenotype in malignant cells which consequently contribute to glioblastoma progression.

Rana Salam
Alexa Saliou
Isabelle Le Roux
ResearchOpen Access27 Jan 2023
Nature Communications

Volume: 14, P: 1-21
Mechanisms and therapeutic implications of hypermutation in gliomas

Temozolomide therapy seems to lead to mismatch repair deficiency and hypermutation in gliomas, but not to an increase in response to immunotherapy.

Mehdi Touat
Yvonne Y. Li
Keith L. Ligon
Research15 Apr 2020
Nature

Volume: 580, P: 517-523
Pan-cancer landscape of AID-related mutations, composite mutations, and their potential role in the ICI response

Isaias Hernández-Verdin
Kadir C. Akdemir
Agustí Alentorn
ResearchOpen Access01 Dec 2022
npj Precision Oncology

Volume: 6, P: 1-14