Nature Search

Cancer biomarkers discovered using pan-cancer plasma proteomic profiling

Proteome profiling of plasma samples in human pan-cancer cohorts reveals patterns of biomarkers for diagnosis.

Lin Bai
Jiacheng Lyu
Chen Ding
Research02 Jul 2025
Nature Biomedical Engineering

P: 1-23
CEACAM1 as a mediator of B-cell receptor signaling in mantle cell lymphoma

Pathological B-cell receptor (BCR) signaling is a key driver of mantle cell lymphoma tumorigenesis. Here, the authors discover that CEACAM1, an immunoglobulin-like transmembrane protein, is essential for a subset of mantle cell lymphoma through activation of the BCR.

Serene Xavier
Vivian Nguyen
Vu N. Ngo
ResearchOpen Access29 May 2025
Nature Communications

Volume: 16, P: 1-18
Toward high-current-density and high-frequency graphene resonant tunneling transistors

2D devices with negative differential resistance are desired for multivalued logic applications, but they are normally limited by low current densities and operational frequency. Here, the authors report graphene/hexagonal boron nitride/graphene resonant tunnelling transistors with room temperature peak current density up to 2700 μA/μm² and operational frequencies up to 11 GHz.

Zihao Zhang
Baoqing Zhang
Aimin Song
ResearchOpen Access23 May 2025
Nature Communications

Volume: 16, P: 1-10
Graphene ballistic nano-rectifier with very high responsivity

The high mobility of graphene has the potential to enable design of devices working in a collisionless regime of carrier transport. Here the authors fabricate a ballistic nano-rectifier based on encapsulated graphene, showing intrinsic performances comparable to those of superconducting bolometers.

Gregory Auton
Jiawei Zhang
Aimin Song
ResearchOpen Access31 May 2016
Nature Communications

Volume: 7, P: 1-6
Flexible indium–gallium–zinc–oxide Schottky diode operating beyond 2.45 GHz

Flexible mobile phones require bendable electronic components that operate at high frequency. Here, the authors demonstrate such a diode made of an amorphous material on a plastic substrate that operates in the frequency bands applicable to cellular communication, Bluetooth, Wi-Fi and GPS.

Jiawei Zhang
Yunpeng Li
Aimin Song
Research03 Jul 2015
Nature Communications

Volume: 6, P: 1-7
ARID1A loss enhances sensitivity to c-MET inhibition by dual targeting of GPX4 and iron homeostasis, inducing ferroptosis

Xu Zhang
Zihuan Wang
Changjie Wu
ResearchOpen Access14 May 2025
Cell Death & Differentiation

P: 1-13
Fully screen-printed paper-based ZnO synaptic transistor arrays for visual perception and neuromorphic computing

Xiaoqian Li
Lin Yi
Aimin Song
ResearchOpen Access13 Jun 2025
npj Flexible Electronics

Volume: 9, P: 1-12
Multiplexed food-borne pathogen detection using an argonaute-mediated digital sensor based on a magnetic-bead-assisted imaging transcoding system

A method for detecting Salmonella enterica subsp. enterica serovar Typhimurium, Staphylococcus aureus and Listeria monocytogenes is developed, enabling simultaneous and rapid artificial-intelligence-assisted food-borne pathogen detection.

Zhipan Wang
Xinrui Cheng
Yiping Chen
Research02 Jan 2025
Nature Food

Volume: 6, P: 170-181
Association between plasma proteomic dynamic changes and metabolic outcomes in patients undergoing bariatric surgery

Candela Diaz-Canestro
Wah Yang
Aimin Xu
Research05 Jun 2025
International Journal of Obesity

P: 1-10
Plasma proteome profiling reveals dynamic of cholesterol marker after dual blocker therapy

Dual blockade therapy is currently being trialled for multiple tumour types, but efficacy is variable. Here, the authors use longitudinal proteomics profiling of 22 patients to develop a predictive model of therapy response.

Jiacheng Lyu
Lin Bai
Chen Ding
ResearchOpen Access08 May 2024
Nature Communications

Volume: 15, P: 1-14
The non-redundant functions of PIWI family proteins in gametogenesis in golden hamsters

The role of PIWI proteins in mammalian reproduction remains poorly understood. Here, using golden hamsters, the authors establish expression profiles for all four PIWIs during gametogenesis and characterize their associated reproductive defects.

Xiaolong Lv
Wen Xiao
Ligang Wu
ResearchOpen Access29 Aug 2023
Nature Communications

Volume: 14, P: 1-16
Targeted degradation via direct 26S proteasome recruitment

Discovery of macrocyclic ligands to the 19S regulatory particle protein PSMD2 enables the synthesis of heterobifunctional molecules that demonstrate proof-of-concept, targeted degradation of BRD4 through direct engagement of the 26S proteasome.

Charlene Bashore
Sumit Prakash
Erin C. Dueber
ResearchOpen Access28 Dec 2022
Nature Chemical Biology

Volume: 19, P: 55-63
The piRNA pathway is essential for generating functional oocytes in golden hamsters

A set of three papers reports that the piRNA pathway is essential for mammalian female fertility based on genetic perturbation experiments performed in golden hamsters.

Hongdao Zhang
Fengjuan Zhang
Jianmin Li
Research06 Sept 2021
Nature Cell Biology

Volume: 23, P: 1013-1022
Extremely Sensitive Dependence of SnO_x Film Properties on Sputtering Power

Yunpeng Li
Qian Xin
Aimin Song
ResearchOpen Access08 Nov 2016
Scientific Reports

Volume: 6, P: 1-9
Multi frequency multi bit amplitude modulation of spoof surface plasmon polaritons by schottky diode bridged interdigital SRRs

Haotian Ling
Baoqing Zhang
Aimin Song
ResearchOpen Access28 Sept 2021
Scientific Reports

Volume: 11, P: 1-8
A Sputtered Silicon Oxide Electrolyte for High-Performance Thin-Film Transistors

Xiaochen Ma
Jiawei Zhang
Aimin Song
ResearchOpen Access11 Apr 2017
Scientific Reports

Volume: 7, P: 1-6
Facile synthesis of diverse graphene nanomeshes based on simultaneous regulation of pore size and surface structure

Jia Zhang
Huaibing Song
Changsheng Xie
ResearchOpen Access26 Aug 2016
Scientific Reports

Volume: 6, P: 1-9
Safety, pharmacokinetics and efficacy of HA121-28 in patients with advanced solid tumors and RET fusion-positive non-small-cell lung cancer: a multicenter, open-label, single-arm phase 1/2 trial

Dan-Yun Ruan
Wen-Wen Huang
Hongyun Zhao
ResearchOpen Access28 Feb 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-12
Rearrangement of mitochondrial tRNA genes in flat bugs (Hemiptera: Aradidae)

Fan Song
Hu Li
Wanzhi Cai
ResearchOpen Access16 May 2016
Scientific Reports

Volume: 6, P: 1-9
Chalcogen passivation: an in-situ method to manipulate the morphology and electrical property of GaAs nanowires

Zai-xing Yang
Yanxue Yin
Johnny C. Ho
ResearchOpen Access02 May 2018
Scientific Reports

Volume: 8, P: 1-9
Genomics and transcriptomics of the Chinese mitten crabs (Eriocheir sinensis)

Nan Yang
Wenjing Li
Shengyan Su
ResearchOpen Access30 Nov 2023
Scientific Data

Volume: 10, P: 1-13
Lowered fasting chenodeoxycholic acid correlated with the decrease of fibroblast growth factor 19 in Chinese subjects with impaired fasting glucose

Jing Zhang
Huating Li
Weiping Jia
ResearchOpen Access20 Jul 2017
Scientific Reports

Volume: 7, P: 1-11

Search

Cancer biomarkers discovered using pan-cancer plasma proteomic profiling

CEACAM1 as a mediator of B-cell receptor signaling in mantle cell lymphoma

Toward high-current-density and high-frequency graphene resonant tunneling transistors

Graphene ballistic nano-rectifier with very high responsivity

Flexible indium–gallium–zinc–oxide Schottky diode operating beyond 2.45 GHz

ARID1A loss enhances sensitivity to c-MET inhibition by dual targeting of GPX4 and iron homeostasis, inducing ferroptosis

Fully screen-printed paper-based ZnO synaptic transistor arrays for visual perception and neuromorphic computing

Multiplexed food-borne pathogen detection using an argonaute-mediated digital sensor based on a magnetic-bead-assisted imaging transcoding system

Association between plasma proteomic dynamic changes and metabolic outcomes in patients undergoing bariatric surgery

Plasma proteome profiling reveals dynamic of cholesterol marker after dual blocker therapy

The non-redundant functions of PIWI family proteins in gametogenesis in golden hamsters

Targeted degradation via direct 26S proteasome recruitment

The piRNA pathway is essential for generating functional oocytes in golden hamsters

Extremely Sensitive Dependence of SnO_x Film Properties on Sputtering Power

Multi frequency multi bit amplitude modulation of spoof surface plasmon polaritons by schottky diode bridged interdigital SRRs

A Sputtered Silicon Oxide Electrolyte for High-Performance Thin-Film Transistors

Facile synthesis of diverse graphene nanomeshes based on simultaneous regulation of pore size and surface structure

Safety, pharmacokinetics and efficacy of HA121-28 in patients with advanced solid tumors and RET fusion-positive non-small-cell lung cancer: a multicenter, open-label, single-arm phase 1/2 trial

Rearrangement of mitochondrial tRNA genes in flat bugs (Hemiptera: Aradidae)

Chalcogen passivation: an in-situ method to manipulate the morphology and electrical property of GaAs nanowires

Genomics and transcriptomics of the Chinese mitten crabs (Eriocheir sinensis)

Lowered fasting chenodeoxycholic acid correlated with the decrease of fibroblast growth factor 19 in Chinese subjects with impaired fasting glucose

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