Nature Search

Evolution and functioning of an X–A balance sex-determining system in hops

On the basis of the whole-genome sequences of cultivated and wild hops, this study describes the evolution of sex chromosomes, including degeneration and dosage compensation, and identifies a candidate gene for the X–A balance sex-determination system in these species.

Takashi Akagi
Tenta Segawa
Eiichiro Ono
Research18 Jun 2025
Nature Plants

P: 1-14
Side-Chain Liquid Crystalline Block Copolymers with Well Defined Structures Prepared by Living Anionic Polymerization IV. Microphase Morphology in Blends with Coil Homopolystyrenes

Tomomichi Itoh
Naoki Tomikawa
Junji Watanabe
Research01 Oct 2001
Polymer Journal

Volume: 33, P: 783-791
Effect of Posterior Pituitary Hormone on the Release of Adrenocorticotrophic Hormone

SHINJI ITOH
AKIRA ARIMURA
Research03 Jul 1954
Nature

Volume: 174, P: 37
Trinucleotide duplex formation inside a confined nanospace under supercooled conditions

The hybridization of DNA in solution is more difficult the shorter the strands become, making trimer duplexes difficult to isolate and study. Here, the authors use a silica pore in supercooled conditions to isolate and study complementary and mismatched trimer DNA duplexes.

Hiroyuki Arafune
Akira Yamaguchi
Norio Teramae
Research13 Oct 2014
Nature Communications

Volume: 5, P: 1-7
Discovery of cometary kilometric radiations and plasma waves at comet Halley

Hiroshi Oya
Akira Morioka
Bruce T. Tsurutani
Research15 May 1986
Nature

Volume: 321, P: 307-310
Erratum: YAP determines the cell fate of injured mouse hepatocytes in vivo

Norio Miyamura
Shoji Hata
Hiroshi Nishina
Amendments and CorrectionsOpen Access07 Aug 2017
Nature Communications

Volume: 8, P: 1
Bach2–Batf interactions control Th2-type immune response by regulating the IL-4 amplification loop

Bach2 limits T cell effector functions. Here the authors show that Bach2–Batf complex antagonizes the recruitment of the Batf–Irf4 complex to AP-1 motifs and suppresses Th2 cytokine production, and describe mechanisms of negative feedback by which Bach2 restricts Baft-mediated Th2 response.

Makoto Kuwahara
Wataru Ise
Masakatsu Yamashita
ResearchOpen Access01 Sept 2016
Nature Communications

Volume: 7, P: 1-13
Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Mammalian genomes are scattered with repetitive sequences, but their biology remains largely elusive. Here, the authors show that transcription can initiate from short tandem repetitive sequences, and that genetic variants linked to human diseases are preferentially found at repeats with high transcription initiation level.

Mathys Grapotte
Manu Saraswat
Charles-Henri Lecellier
ResearchOpen Access02 Jun 2021
Nature Communications

Volume: 12, P: 1-18
TAG-1–assisted progenitor elongation streamlines nuclear migration to optimize subapical crowding

The authors show that shortening of the basal process in neural progenitor cells by depletion of TAG-1 results in overcrowding in the periventricular space and, eventually, delamination and aberrant migration. These results suggest that one of the functions of interkinetic nuclear migration is to prevent progenitor congestion and mechanical stress.

Mayumi Okamoto
Takashi Namba
Takaki Miyata
Research22 Sept 2013
Nature Neuroscience

Volume: 16, P: 1556-1566
Correction: Corrigendum: Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3

Yasuhito Yahara
Hiroshi Takemori
Noriyuki Tsumaki
Amendments and CorrectionsOpen Access27 Jun 2016
Nature Communications

Volume: 7, P: 1-2
Crystal Orbital Study on Ferromagnetic State of Poly(m-aniline)

Kazunari Yoshizawa
Akira Takata
Tokio Yamabe
Research01 Sept 1992
Polymer Journal

Volume: 24, P: 857-864
Synthesis and Characterization of UV-Induced Interpenetrating Polymer Network (IPN) Structure of Poly(urethane acrylate) (UA Polymer)/Silica Hybrids

Tomoki Ogoshi
Yoshiki Chujo
Akira Esaki
Research08 Sept 2005
Polymer Journal

Volume: 37, P: 686-693
Genome editing in plants by engineered CRISPR–Cas9 recognizing NG PAM

The engineered Streptococcus pyogenes Cas9 variant SpCas9-NGv1, known to recognize relaxed NG protospacer adjacent motifs (PAMs) in human cells, can also mediate targeted mutagenesis with NG PAMs in rice and Arabidopsis. When fused with cytidine deaminase, it mediates C-to-T substitutions.

Masaki Endo
Masafumi Mikami
Seiichi Toki
Research10 Dec 2018
Nature Plants

Volume: 5, P: 14-17
Latitudinal patterns in stabilizing density dependence of forest communities

An analysis of tree survival data from forest sites worldwide shows that in the tropics, rare tree species experience stronger stabilizing density dependence than common species, wheras no correlation of stabilizing density dependence and abundance exists in the temperate zone.

Lisa Hülsmann
Ryan A. Chisholm
Florian Hartig
ResearchOpen Access28 Feb 2024
Nature

Volume: 627, P: 564-571
YAP determines the cell fate of injured mouse hepatocytes in vivo

Senescent and injured cells affect tissue functions and can drive tumorigenesis. Thus, efficient elimination of these cells is pivotal for tissue integrity. Here Miyamuraet al. show that YAP acts as a cellular stress sensor and promotes the elimination of damaged cells to maintain tissue homeostasis.

Norio Miyamura
Shoji Hata
Hiroshi Nishina
ResearchOpen Access06 Jul 2017
Nature Communications

Volume: 8, P: 1-10
Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice

Masao Murakami
Takeshi Tsubata
Tasuku Honjo
Research07 May 1992
Nature

Volume: 357, P: 77-80
Prevalence of the mitochondrial 1555 A>G and 1494 C>T mutations in a community-dwelling population in Japan

Yasunori Maeda
Akira Sasaki
Atsushi Matsubara
ResearchOpen Access18 Sept 2020
Human Genome Variation

Volume: 7, P: 1-6
Tropical tree ectomycorrhiza are distributed independently of soil nutrients

Analysing data on the relative abundance of basal area of ectomycorrhizal trees from lowland tropical forests, the authors show that their distribution and abundance are independent of soil quality.

José A. Medina-Vega
Daniel Zuleta
Stuart J. Davies
Research10 Jan 2024
Nature Ecology & Evolution

Volume: 8, P: 400-410
N-glycan-modified α-L-iduronidase produced by transgenic silkworms ameliorates clinical signs in a Japanese macaque with mucopolysaccharidosis I

Shinoda and Kitakaze et al. prepared recombinant hIDUA from transgenic silkworm cocoons and transglycosylated to mannose-6-phosphate- or α2,6-sialyl glycan-type using ENGases. These enzymes were administrated to a mucopolysaccharidosis type I macaque and succeeded in improving the clinical signs and reducing the urinary glycosaminoglycan levels.

Chika Shinoda
Keisuke Kitakaze
Kohji Itoh
ResearchOpen Access18 Apr 2025
Communications Medicine

Volume: 5, P: 1-14
Control of cell polarity and motility by the PtdIns(3,4,5)P₃ phosphatase SHIP1

Miki Nishio
Ken-ichi Watanabe
Takehiko Sasaki
Research17 Dec 2006
Nature Cell Biology

Volume: 9, P: 36-44
Contribution of Ryugu-like material to Earth’s volatile inventory by Cu and Zn isotopic analysis

A comparison of copper and zinc isotopic measurements between the Ryugu samples and various carbonaceous chondrites excludes any genetic link between the two except for the CI (Ivuna-type) chondrites. Ryugu-like material might have accounted for ~5% of Earth’s mass.

Marine Paquet
Frederic Moynier
Hisayoshi Yurimoto
Research12 Dec 2022
Nature Astronomy

Volume: 7, P: 182-189
Multicolour photochromism of TiO₂ films loaded with silver nanoparticles

Yoshihisa Ohko
Tetsu Tatsuma
Akira Fujishima
Research15 Dec 2002
Nature Materials

Volume: 2, P: 29-31
Mechanically driven ATP synthesis by F₁-ATPase

Hiroyasu Itoh
Akira Takahashi
Kazuhiko Kinosita Jr
Research29 Jan 2004
Nature

Volume: 427, P: 465-468
Direct observation of DNA rotation during transcription by Escherichia coli RNA polymerase

Yoshie Harada
Osamu Ohara
Kazuhiko Kinosita Jr
Research04 Jan 2001
Nature

Volume: 409, P: 113-115
Application of Poly(vinylidene fluoride) and Poly(methyl methacrylate) Blends to Optical Material

Akira Tanaka
Hisashi Sawada
Yuji Kojima
Research01 Jun 1990
Polymer Journal

Volume: 22, P: 463-467
Carbonate record of temporal change in oxygen fugacity and gaseous species in asteroid Ryugu

The asteroid Ryugu experienced aqueous alteration under changing temperature and redox conditions, according to an isotopic analysis of secondary calcite and dolomite grains in samples from Ryugu obtained by the Hayabusa2 spacecraft.

Wataru Fujiya
Noriyuki Kawasaki
Hisayoshi Yurimoto
Research10 Jul 2023
Nature Geoscience

Volume: 16, P: 675-682
The interspecific growth–mortality trade-off is not a general framework for tropical forest community structure

Using demographic data for 1,111 tree species across ten tropical forests, the authors test the generality of the growth–mortality trade-off, finding that it holds in undisturbed but not disturbed forests.

Sabrina E. Russo
Sean M. McMahon
Jess K. Zimmerman
Research16 Nov 2020
Nature Ecology & Evolution

Volume: 5, P: 174-183
Activation of the hypothalamic feeding centre upon visual prey detection

Hypothalamus is important for regulating feeding behaviour. Here the authors report genetic identification of neurons in the pretecto-hypothalamic circuit, and their causal involvement in prey detection and prey capture, using a combination of functional imaging and ablation studies in freely swimming zebrafish larvae.

Akira Muto
Pradeep Lal
Koichi Kawakami
ResearchOpen Access20 Apr 2017
Nature Communications

Volume: 8, P: 1-10
Does the flushing response modify the relationship between alcohol intake and hypertension in the Japanese population? NIPPON DATA2010

Mana Kogure
Naho Tsuchiya
Katsuyuki Miura
Research12 May 2016
Hypertension Research

Volume: 39, P: 670-679
Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Mathys Grapotte
Manu Saraswat
Charles-Henri Lecellier
Amendments and CorrectionsOpen Access01 Mar 2022
Nature Communications

Volume: 13, P: 1
Gapless spin liquid in a square-kagome lattice antiferromagnet

There exist many theoretical models of frustrated quantum magnetism, most of which lack convincing experimental realisations. Here the authors combine several experimental methods to argue that KCu₆AlBiO₄(SO₄)₅Cl behaves as a square-kagome-lattice quantum Heisenberg antiferromagnet.

Masayoshi Fujihala
Katsuhiro Morita
Kenji Nakajima
ResearchOpen Access09 Jul 2020
Nature Communications

Volume: 11, P: 1-7
Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians

The microbiota of centenarians (aged 100 years and older) comprise gut microorganisms that are capable of generating unique secondary bile acids, including isoallolithocholic acid, a bile acid with potent antimicrobial effects against Gram-positive—but not Gram-negative—multidrug-resistant pathogens.

Yuko Sato
Koji Atarashi
Kenya Honda
Research29 Jul 2021
Nature

Volume: 599, P: 458-464
Author Correction: Contribution of Ryugu-like material to Earth’s volatile inventory by Cu and Zn isotopic analysis

Marine Paquet
Frederic Moynier
Hisayoshi Yurimoto
Amendments and Corrections14 Mar 2023
Nature Astronomy

Volume: 7, P: 633
Structure of Nascent Microbial Cellulose I. Effects of Methyl and Methoxy Groups of Direct Blue 1 and 53 on Nascent Microbial Cellulose

Md Ibrahim H Mondal
Akira Kai
Research01 Feb 1998
Polymer Journal

Volume: 30, P: 78-83
Study of Glass Transition and Partial Melting in Melt-crystallized Poly(oxymethylene) by X-Ray Small-angle Scattering

Yuji Aoki
Akira Nobuta
Motozo Kaneko
Research01 Jul 1971
Polymer Journal

Volume: 2, P: 502-508
Association of mitochondrial DNA haplogroup and hearing impairment with aging in Japanese general population of the Iwaki Health Promotion Project

Shiori Miura
Akira Sasaki
Atsushi Matsubara
ResearchOpen Access17 Jan 2022
Journal of Human Genetics

Volume: 67, P: 369-375
Clinical utility of simple subjective gait speed for the risk stratification of heart failure in a primary prevention setting

Kensuke Ueno
Hidehiro Kaneko
Issei Komuro
ResearchOpen Access08 Jul 2022
Scientific Reports

Volume: 12, P: 1-8
Inflammation-free, gas-permeable, lightweight, stretchable on-skin electronics with nanomeshes

Breathable and stretchable fibrous mesh electrical interconnects directly attached to human skin can serve as components of on-skin sensors.

Akihito Miyamoto
Sungwon Lee
Takao Someya
Research17 Jul 2017
Nature Nanotechnology

Volume: 12, P: 907-913
Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3

Therapies are needed for the prevention of chondrocyte hypertrophy and thinning of articular cartilage, features of osteoarthritic joint destruction. Here, the authors show that interfering with Sik3 signalling can increase the size of the chondrocyte population and reduce severity of a surgically induced mouse model of osteoarthritis.

Yasuhito Yahara
Hiroshi Takemori
Noriyuki Tsumaki
ResearchOpen Access24 Mar 2016
Nature Communications

Volume: 7, P: 1-14
Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11

This report identifies PICT1 as a new regulator of p53. PICT1 binds the ribosomal protein RPL11 and prevents its release from the nucleolus, precluding RPL11 from inhibiting MDM2 activity. Loss of PICT1 increases p53 abundance and protects from tumorigenesis in mice. PICT1 is also a prognostic marker in human cancers. This p53-dependent protumorigenic function is in contrast with previous reports suggesting a tumor-suppressor role for PICT1.

Masato Sasaki
Kohichi Kawahara
Akira Suzuki
Research31 Jul 2011
Nature Medicine

Volume: 17, P: 944-951
Skewed electronic band structure induced by electric polarization in ferroelectric BaTiO₃

Norihiro Oshime
Jun Kano
Hitoshi Osawa
ResearchOpen Access01 Jul 2020
Scientific Reports

Volume: 10, P: 1-7
Mitochondrial function provides instructive signals for activation-induced B-cell fates

Cell fate choices are often based on amplification of noise. Here the authors show that small initial differences in mitochondrial reactive oxygen species lead to bigger changes in mitochondrial mass and membrane potential, which then determine plasma cell fate choice of activated B cells.

Kyoung-Jin Jang
Hiroto Mano
Manabu Sugai
ResearchOpen Access10 Apr 2015
Nature Communications

Volume: 6, P: 1-13
An atlas of human long non-coding RNAs with accurate 5′ ends

A catalogue of human long non-coding RNA genes and their expression profiles across samples from major human primary cell types, tissues and cell lines.

Chung-Chau Hon
Jordan A. Ramilowski
Alistair R. R. Forrest
Research01 Mar 2017
Nature

Volume: 543, P: 199-204
Complete sequencing and characterization of 21,243 full-length human cDNAs

Toshio Ota
Yutaka Suzuki
Sumio Sugano
Research21 Dec 2003
Nature Genetics

Volume: 36, P: 40-45
Printable elastic conductors by in situ formation of silver nanoparticles from silver flakes

Printing and heating of a fluorinated elastomer mixed with silver flakes, a fluorine surfactant and methylisobutylketone leads to the formation of in situ silver nanoparticles, which boost the conductivity of this highly stretchable composite material.

Naoji Matsuhisa
Daishi Inoue
Takao Someya
Research15 May 2017
Nature Materials

Volume: 16, P: 834-840
SM-216601, a Novel Parenteral 1β-Methylcarbapenem: Structure-activity Relationships of Antibacterial Activity and Neurotoxicity in Mice

Yutaka Ueda
Masanori Itoh
Makoto Sunagawa
Research01 Feb 2005
The Journal of Antibiotics

Volume: 58, P: 118-140
Pulmonary inflammation and cytokine dynamics of bronchoalveolar lavage fluid from a mouse model of bronchial asthma during A(H1N1)pdm09 influenza infection

Yousuke Fujimoto
Shunji Hasegawa
Shouichi Ohga
ResearchOpen Access22 Aug 2017
Scientific Reports

Volume: 7, P: 1-10
Orbital-specific Tunability of Many-Body Effects in Bilayer Graphene by Gate Bias and Metal Contact

Hirokazu Fukidome
Masato Kotsugi
Toyohiko Kinoshita
ResearchOpen Access16 Jan 2014
Scientific Reports

Volume: 4, P: 1-5
Phosphorylated retinoblastoma protein stimulates DNA polymerase α

Masaharu Takemura
Tomotaka Kitagawa
Shonen Yoshida
Research13 Nov 1997
Oncogene

Volume: 15, P: 2483-2492
Cloning and characterization of NE-dlg: a novel human homolog of the Drosophila discs large (dlg) tumor suppressor protein interacts with the APC protein

Keishi Makino
Hiroaki Kuwahara
Hideyuki Saya
Research22 May 1997
Oncogene

Volume: 14, P: 2425-2433

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